Results 41 to 50 of about 418,767 (267)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Archives of Mechanics, 2014 The aim of this paper is to study the effect of hydrogen injection into natural gas transient flows on the mechanical strength of natural gas pipelines.
S. Elaoud, B. Abdulhay, E. Hadj-Taieb
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Zhileng xuebao, 2016 The reed type valve is a key component of reciprocating compressors affecting the efficiency and reliability of the machines. This paper analyzed the flow characteristic firstly, and then simulated the distributions of pressure field and velocity field ...
Wang Feng +3 more
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Energy Science & Engineering, 2022 Pulse injection can reduce the maximum operating pressure at the wellhead, which is conducive to solving the operational difficulties caused by the high breakdown pressure.
Ge Zhu, Shimin Dong, Biao Ma
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Transient Measurements in Rate Controlled Rheometers: A New Method of Standardization
Applied Rheology, 2000 Rheological measurements in response to transient shear rate exhibit coupling effects between mechanical characteristics of rheometer and unsteady (thixotropic and viscoelastic) properties of fluid.
Talbi-Boucenna Imane, Quemada Daniel
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Fluids, 2020 Aerodynamic development for road vehicles is usually carried out in a uniform steady-state flow environment, either in the wind tunnel or in Computational Fluid Dynamics (CFD) simulations.
Xiao Fei +4 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source