Results 51 to 60 of about 697,673 (264)

Intelligent Automation Improved Efficiency in Pharmacovigilance Safety Signal Assessment

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacovigilance is the science involving the detection, assessment, understanding, and prevention of adverse events associated with drugs, biologics, or medical devices. In pharmacovigilance, information that suggests a new potential causal relationship between an intervention and an adverse event is called a safety signal. Following their detection,
Jeffrey Warner, Luis Henrique De Souza Teodoro, Anaclara Prada Jardim, Claudia Albera   +3 more
wiley   +1 more source

Cost-Effectiveness of Radiofrequency Ablation for Benign Non-Functioning Thyroid Nodules: A Systematic Review. [PDF]

Clin Otolaryngol
ABSTRACT Purpose This systematic review tests the hypothesis that radiofrequency ablation (RFA) for benign non‐functioning thyroid nodules is associated with favourable cost‐effectiveness compared with surgery. Materials and Methods A systematic literature search of multiple databases (Embase, Medline, Web of Science, and Cochrane Central) was ...
van Dijk SPJ, Blanco MMK, Akhavan A, McMullin JL, Gazelle GS, Jalali MS, Chhatwal J, Hu Y, van Ginhoven TM, Gartland RM, Cunningham C.   +10 more
europepmc   +2 more sources

Predictive factors of permanent versus transient congenital hypothyroidism: a pragmatic cohort study [PDF]

Annals of Pediatric Endocrinology & Metabolism
Purpose To identify clinical predictors of permanent congenital hypothyroidism (PCH) and transient congenital hypothyroidism (TCH). Methods This retrospective cohort study enrolled neonates with risk factors for congenital hypothyroidism as diagnosed by ...
Niki Dermitzaki, Vasileios Giapros, Marianna Deligeorgopoulou, Vasiliki Rengina Tsinopoulou, Eleni Kotanidou, Maria Baltogianni, Foteini Balomenou, Anastasios Serbis   +7 more
doaj   +1 more source

Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]

, 2013
Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core  

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka, Johann Kornowski, Elena Laakmann, Barbara Schmalfeldt, Tim Zell, Glenn Geidel, Christoffer Gebhardt, Pia Roser, Volkmar Müller, Julian Kött   +9 more
wiley   +1 more source

Assessment of Thyroid Uptake Ratio Values in a Normal Population. Establishment of Normal Reference Values for 99mTc‐Pertechnetate Thyroid Uptake in an Australian Population

Journal of Medical Radiation Sciences, EarlyView.
An Australian first, this study examined normal reference ranges for 99mTc‐pertechnetate thyroid uptake. Through a retrospective and prospective analysis, this study found a new reference range of 0.4%–2.4%. The findings suggest that locally derived reference values may differ from historical data and highlight the importance of region‐specific ...
Bethany Wornes, Amalia Karahalios, Melanie Tempest   +2 more
wiley   +1 more source

Three-year follow-up of children with abnormal newborn screening results for congenital hypothyroidism

Pediatrics and Neonatology, 2017
To analyze predictive factors suggesting transient congenital hypothyroidism (TCH) compared to permanent congenital hypothyroidism (PCH) or transient thyroid function test (TFT) abnormalities among children who had positive screening results at our ...
Min-Jae Kang, Hye-Rim Chung, Yeon-Joung Oh, Young-Suk Shim, Seung Yang, Il-Tae Hwang   +5 more
doaj   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Anna Maria Heikkinen, Hanna Lähteenmäki, Saila Pakarinen, Ismo T. Räisänen, Timo Sorsa, Tommi Pätilä   +9 more
wiley   +1 more source

Prevalence of Transient and Permanent Congenital Hypothyroidism in Mazandaran Province

Journal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Congenital hypothyroidism (CH) is one of the most common preventable causes of mental disabilities. The present study was conducted to determine the prevalence of permanent and transient congenital hypothyroidism in Mazandaran ...
zahra Beheshti, Rozita Rezaei, Abbas Alipour, Mehrnoosh Kosarian, sussan saatsaz   +4 more
doaj  

Mutations and phenotypic characteristics in transient and permanent congenital hypothyroidism: an analysis of literature data.docx

, 2019
Supplemental data of study: Mutations and phenotypic characteristics in transient and permanent congenital hypothyroidism: an analysis of literature ...
Bin Yu (14464), Fang Guo (105824), Wei Long (7302881), Huaiyan Wang (7302883), Ying Wang (11406)   +4 more
core   +1 more source