Results 71 to 80 of about 1,279,230 (261)

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

No evidence that severity of stroke in internal carotid occlusion is related to collateral arteries [PDF]

, 2006
Background/AimThe neurological effects of internal carotid artery (ICA) occlusion vary between patients. The authors investigated whether the severity of symptoms in a large group of patients with ipsilateral or/and contralateral ICA occlusion at ...
?, ?, Wardlaw, J M, Mead, G E, Dennis, M S, Lewis, S C   +4 more
core   +1 more source

The role of transient ischemic attacks in the occurrence of cognitive impairment [PDF]

Саратовский научно-медицинский журнал, 2016
The information about cognitive impairment of patient, suffered from transient ischemic attack (TIA) is summarized on the base of Russian and foreign literature.
Maleina A.U., Kolokolov O.V., Lukina E.V.   +2 more
doaj  

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Elevated serum neopterin and homocysteine increased the risk of ischemic stroke in patients with transient ischemic attack

Pteridines, 2019
Objective: To investigate the correlation between serum neopterin, homocysteine (Hcy) and the risk of developing ischemic stroke (IS) in patients with transient ischemic attack (TIA).
Xie Jing, Qiu Xiandi, Ji Chunli, Liu Chunhong, Wu Yueming   +4 more
doaj   +1 more source

Three months prognosis of transient ischemic attack (TIA) in Erbil Governorate [PDF]

, 2014
Background and objective: A transient ischemic attack is a brief episode of neurological dysfunction resulting from focal cerebral ischemia not associated with permanent cerebral infarction. Transient ischemic attack carries a substantial short-term risk
Ahmed, Abdullah Faqiyzadin
core  

Acute Treatment of Transient Ischemic Attack and Minor Stroke

, 2018
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Rothwell, PM, Pendlebury, ST, Lau, GKK
core   +1 more source

Contemporary prognosis of transient ischemic attack patients:a systematic review and meta-analysis [PDF]

, 2019
Background: Transient ischemic attacks are common and place patients at risk of subsequent stroke. The 2007 EXPRESS and SOS-TIA studies demonstrated the efficacy of rapid treatment initiation.
Levi, Christopher (R19066), Quain, Debbie, Attia, John, Najib, Nashwa, Magin, Parker J, Levi, Christopher R, Oldmeadow, Christopher, Garcia-Esperon, Carlos, Magin, Parker, Lasserson, Daniel   +9 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source