Results 181 to 190 of about 316,285 (309)
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Virtual State Coupled Sliding Mode Control: An Energy Exchange Approach with Tunable Performance Trade-Off. [PDF]
Wang J, Wang J, Jing J, Zhao C, Zhang L.
europepmc +1 more source
Nonlinear stability of liquid flow down an inclined plan
A modified energy method is proposed to study the nonlinear stability of Poiseuille flow with upper free boundary St, down an inclined plane. Sufficient conditions on Reynolds, and Weber numbers, on the slope of the plane, together with the periodicity ...
Padula, Mariarosaria
core
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Transient dynamics and nonlinear fitness: A matrix approach to pulse and press perturbation. [PDF]
Jaggi H +5 more
europepmc +1 more source
A Practical Method for Power Systems Transient Stability and Security
Stability analysis methods may be categorized by two major stability analysis methods: small-signal stability and transient stability analyses. Transient stability methods are further categorized into two major categories: numerical methods based on ...
Al Marhoon, Hussain Hassan
core
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
The Rhythmic Embodied Perception Framework of breath, brain, and perception. [PDF]
Andrews R, Dockree PM.
europepmc +1 more source
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source

