Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Coupling of Transport and Chemical Processes in Catalytic Combustion [PDF]
, 1983 Catalytic combustors have demonstrated the ability to operate efficiently over a much wider range of fuel air ratios than are imposed by the flammability limits of conventional combustors.
Bracco, F. V. +5 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Transient Stability Assessment Method for Multi-machine Power Systems Considering Dense Channels
Zhongguo dianliTo improve the accuracy and efficiency of power system transient stability assessment, a transient stability assessment method for multi-machine power system considering dense channel based on deep transfer is proposed. Firstly, a new transient stability
Xuejun WANG +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Revista Científica de Ingeniería Energética, 2010 In Cuba, from the seventies of the past century, different algorithms to study stationary and transientregimes of the Cuban Electric System were developed. Those algorithms and computer programs werefocused in the study of transient stability. Currently,
Zaid García ; et al.
doaj
Poppet valve control of throat stability bypass to increase stable airflow range of a Mach 2.5. inlet with 60 percent internal contraction [PDF]
The throat of a Mach 2.5 inlet with a coldpipe termination was fitted with a stability-bypass system. System variations included several stability bypass entrance configurations. Poppet valves controlled the bypass airflow. The inlet stable airflow range
Mitchell, G. A., Sanders, B. W.
core +1 more source
Transient Stability Assessment of Hybrid Distributed Generation and its Impact on Critical Clearing Time and Oscillation Duration Considering its Complementary Nature [PDF]
, 2018 Presently, the grid accommodates several mixed energies so as to improve power generation and cater for demand which is ever increasing. These energy sources interact with each other and with the existing grid.
Olulope, P. K. (P)
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
IEEE AccessIn novel power systems, complex coupling among stations and devices with diverse synchronization mechanisms profoundly impacts system stability.
Xinyu Guo +4 more
doaj +1 more source