Results 91 to 100 of about 1,352,157 (309)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Impacts of Integration of Wind Farms on Power System Transient Stability

Applied Sciences, 2018
To compensate for the ever-growing energy gap, renewable resources have undergone fast expansions worldwide in recent years, but they also result in some challenges for power system operation such as the static security and transient stability issues. In
Shiwei Xia, Qian Zhang, S.T. Hussain, Baodi Hong, Weiwei Zou   +4 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Transient Synchronization Stability in Grid-Following Converters: Mechanistic Insights and Technological Prospects—A Review

Energies
This paper investigates the transient synchronization stability mechanisms and technological advancements associated with grid-following (GFL) converters, providing a systematic review of the current research landscape and future directions in this field.
Yang Liu, Lin Zhu, Xinya Xu, Dongrui Li, Zhiwei Liang, Nan Ye   +5 more
doaj   +1 more source

Transient Stability Analysis of DFIGS Using Eigenvalues Analysis [PDF]

Bulletin of the Faculty of Engineering. Mansoura University, 2020
Sobhy Abdelkader, Ahmed Hatata, Mahmoud Abdelbacky   +2 more
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A Coupling‐Factor‐Based Nonlinear Decoupling Method for Transient Operation Analysis of LCL‐Filtered Grid‐Connected VSC

IET Renewable Power Generation
In light of the exponential growth in renewable energy generation, voltage source converters (VSCs) have garnered extensive attention, particularly concerning control methodologies and steady‐state operation analysis.
Pengcheng Yang, Hongda Cai, Jing Li, Yue Li   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Transient Stability Analysis and Emergency Generator Tripping Control Based on Spatio-Temporal Graph Deep Learning

Energies
This paper addresses the challenge of achieving fast and accurate transient stability analysis and emergency control in power systems, which are crucial for reliable grid operation under disturbances.
Shuaibo Wang, Jie Zeng, Jie Zhang, Zhuohang Liang, Yihua Zhu, Shufang Li   +5 more
doaj   +1 more source