Results 81 to 90 of about 1,352,157 (309)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Transient stability analysis and enhancement of wind farm integrated VSC-HVDC system

CSEE Journal of Power and Energy Systems
Following severe faults in wind farm integrated voltage source converter (VSC) based high-voltage direct current (HVDC) system, wind turbines (WTs) may lose synchronization with wind farm side VSC (WFVSC), which jeopardizes the reliable delivery and ...
Guanqun Li, Hua Ye, Junru Chen, Qianying Mou   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Independent Microgrid Transient Stability Evaluation Model Based on a Message Passing Graph Neural Network

IET Renewable Power Generation
In isolated microgrids, virtual synchronous generators (VSGs) are utilized to enhance frequency stability. However, the presence of these generators can lead to undesirable levels of voltage or current during transient angle instability.
Yuntao Ju, Ziyi Li
doaj   +1 more source

Efficient Transient Stability Analysis of Electrical Power System Based on a Spatially Paralleled Hybrid Approach

IEEE Transactions on Industrial Informatics, 2019
With continually increasing complexities of power systems, transient stability analysis as an important task for system security operation becomes very time consuming and thus an efficient analysis tool is urgently needed.
S. Xia, S. Bu, Junjie Hu, B. Hong, Zhizhong Guo, Dongying Zhang   +5 more
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Transient Stability Analysis and Enhancement Strategies for AC Side of Hydro-Wind-PV VSC-HVDC Transmission System

Applied Sciences
To analyze and enhance the transient stability of a hydro-wind-PV VSC-HVDC transmission system, this paper establishes a transient stability analytical model and proposes strategies for stability improvement.
Xinwei Li, Yanjun Ma, Jie Fang, Kai Ma, Han Jiang, Zheren Zhang, Zheng Xu   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Electromagnetic Transient-Transient Stability Analysis Hybrid Real-Time Simulation Method of Variable Area of Interest

Energies, 2018
To make the object of electromagnetic transient (EMT) simulation flexible to change, the authors propose using the method of electromagnetic transient-transient stability analysis (TSA) hybrid real-time simulation of the variable area of interest.
Bingda Zhang, Shipei Nie, Zhao Jin
doaj   +1 more source