Results 121 to 130 of about 1,048,939 (345)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Bilateral international migration flow estimates by type of move (outward, return or transit) for 200 countries (1990-1995 to 2015-2020)

, 2022
Guy Abel
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Optimal coordination for an integrated multimodal and multi-operator transit system [PDF]

, 2008
Shoujie Li
openalex   +1 more source

Transit-Oriented Inclusionary Mixed-Use Development

, 2021

openalex   +2 more sources

Transit Photometry as an Exoplanet Discovery Method

, 2018
Photometry with the transit method has arguably been the most successful exoplanet discovery method to date. A short overview about the rise of that method to its present status is given.
A Collier Cameron, A Collier Cameron, A Giménez, A Léger, A Santerne, A Shporer, A Udalski, AMS Smith, Andrew Collier Cameron, B Tingley, BE McArthur, C Elachi, C Moutou, C Régulo, CA Haswell, D Bayliss, D Charbonneau, D Charbonneau, D Koch, D Queloz, D. J. Christian, DL Pollacco, DM Kipping, DW Latham, DW Latham, F Bouchy, F Pont, FT O’Donovan, G Kovács, G Kovács, G Torres, G Torres, G Torres, GR Ricker, GW Henry, GÁ Bakos, H Rauer, H. Parviainen, HJ Deeg, HJ Deeg, HJ Deeg, HJ Deeg, IAG Snellen, J Scalo, J. Cabrera, JA Dittmann, Jason F. Rowe, Jeffrey L. Coughlin, JJ Lissauer, JJ Lissauer, JJ Lissauer, JM Almenara, JM Jenkins, JM Jenkins, JM Jenkins, JN Winn, JT Wright, K Horne, K Mandel, KC Sahu, LR Doyle, M Gillon, M Konacki, MN Günther, MN Günther, NM Batalha, O Struve, O Tamuz, P Barge, PJ Wheatley, PJ Wheatley, R Alonso, R Alonso, R Alonso, RF Díaz, RL Gilliland, RL Gilliland, S Aigrain, S Aigrain, S Jha, S Seager, SB Howell, Smith AMS WASP Consortium, TD Morton, TD Morton, TG Beatty, TM Brown, WJ Borucki, ZK Berta   +88 more
core   +1 more source

Central Places of Transit Riders: A Visual Story of Brisbane, Australia

Regional Studies, Regional Science, 2016
This study uses smartcard data to quantify and visualize the most popular destinations (‘central places’) and corridors of transit riders in Brisbane, an emerging global city in Queensland, Australia.
Ming Wei, Jiangping Zhou
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

RICHMOND’S JOURNEY-TO-WORK TRANSIT TRIP-MAKING ANALYSIS [PDF]

This paper uses the 2000 Census Transportation Planning Package data to conduct a journey-to-work transit trip-making analysis for the City of Richmond, Virginia.
I-Shian SUEN, Xueming CHEN
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source