California Voting and Suburbanization Patterns: Implications for Transit Policy, MTI Report 12-05 [PDF]
Public transit is an environmentally friendly transportation mode that usually focuses on transporting people within and to the city center. However, over the last 60 years, population and employment has been suburbanizing.
Holian, Matthew J., Kahn, Matthew E.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
ERRATUM: “TRANSITS AND OCCULTATIONS OF AN EARTH-SIZED PLANET IN AN 8.5 hr ORBIT” (2013, ApJ, 774, 54) [PDF]
Roberto Sanchis-Ojeda +6 more
openalex +1 more source
Transit in Washington, D.C.: Current Benefits and Optimal Level of Provision [PDF]
The discrepancy between transit’s large share of local transportation resources and its generally low share of local trips has raised questions about the use of scarce transportation funds for this purpose.
Bagliano, Andrew +4 more
core
What do Americans Think About Federal Tax Options to Support Public Transit, Highways, and Local Streets and Roads? Results from Year Four of a National Survey, MTI Report 12-07 [PDF]
This report summarizes the results of year four of a national random-digit-dial public opinion poll asking 1,501 respondents if they would support various tax options for raising federal transportation revenues, with a special focus on understanding ...
Agrawal, Asha Weinstein, Nixon, Hilary
core +1 more source
Water is critical for survival and thirst is a powerful way of ensuring that fluid levels remain in balance. Overconsumption, however, can have deleterious effects, therefore optimization requires a need to balance the drive for water with the satiation of that water drive.
Jessica Santollo, Derek Daniels
openaire +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The TESS-Keck Survey. XI. Mass Measurements for Four Transiting Sub-Neptunes Orbiting K Dwarf TOI–1246 [PDF]
Emma V. Turtelboom +80 more
openalex +1 more source

