Results 221 to 230 of about 1,048,939 (345)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Visual inspection of potential exocomet transits identified through machine learning and statistical methods

open access: green
D. V. Dobrycheva   +6 more
openalex   +1 more source

WASP-41b: A Transiting Hot Jupiter Planet Orbiting a Magnetically Active G8V Star [PDF]

open access: bronze, 2011
P. F. L. Maxted   +15 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The Evolution of Irradiated Planets: Application to Transits [PDF]

open access: bronze, 2004
G. Chabrier   +4 more
openalex   +1 more source

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