Results 71 to 80 of about 308,788 (299)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Cooperative Data Mining Approach for Potential Urban Rail Transit Demand Using Probe Vehicle Trajectories

open access: yesIEEE Access, 2020
Promoting the use of public transportation is an important approach to develop sustainable mobility. However, lots of potential users of public transportation chose taxi, a semi-private mode for convenience.
Xiaoyun Cheng, Kun Huang, Lei Qu, Li Li
doaj   +1 more source

The Stability of downtown parking and traffic congestion [PDF]

open access: yes, 2008
In classical traffic flow theory, there are two velocities associated with a given level of traffic flow. Following Vickrey, economists have termed travel at the higher speed congested travel and at the lower speed hypercongested travel.
Arnott, Richard, İnci, Eren, Inci, Eren
core   +11 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Dealing with the Empty Vehicle Movements in Personal Rapid Transit System with Batteries Constraints in a Dynamic Context

open access: yesJournal of Advanced Transportation, 2017
The Personal Rapid Transit is a new emergent transportation tool. It relies on using a set of small driverless electric vehicles to transport people on demand.
Ezzeddine Fatnassi   +2 more
doaj   +1 more source

Nuclear transitions on demand

open access: yesEPJ Web of Conferences
I show a way to tune photo-nuclear cross section effectively and therefore achieve nuclear transitions "on demand". The method is based on combinatorial enhancement of multiphoton processes under intense conditions. Taking advantage of recent advances in high-power laser systems (HPLS) and nuclear structure calculations, efficient ...
openaire   +2 more sources

The role of Turkey in the European energy market [PDF]

open access: yes, 2012
The essay in this Med-Agenda aims to examine the role of Turkey in the global energy market within the context of European Energy Security. In the essay we have attempted to answer the following questions: What will the future role of Turkey be in the ...
Yılmaz, Bahri, Yilmaz, Bahri
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Simplified model of local transit services

open access: yesEuropean Journal of Transport and Infrastructure Research, 2014
This paper discusses the development of a simplified model to efficiently represent local public transportation services in a large-scale travel demand model.
Giovanni Circella   +4 more
doaj   +1 more source

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