Results 101 to 110 of about 313,243 (217)

Automated 3D portal dosimetry for large-scale plan-specific QA in external beam radiotherapy [PDF]

External beam radiation therapy (EBRT) delivers targeted radiation from outside the body to destroy cancer cells. Plan-specific quality assurance (PSQA) ensures accurate dose delivery for each treatment.
Olaciregui Ruiz, I.
core   +4 more sources

Pulse‑level characterization of low monitor unit deliveries on a modern linear accelerator using a plastic scintillation detector

Journal of Applied Clinical Medical Physics, Volume 27, Issue 7, July 2026.
Abstract Background Variability in low monitor unit (MU) deliveries has been previously documented, but the underlying pulse‑level behavior has not been fully described due to the integrating nature of most conventional detectors. A plastic scintillation detector (PSD) enables direct visualization of MU microstructure by isolating individual linac ...
Andrew J. White, Poonam Yadav, Indra J. Das, Ahtesham U. Khan   +3 more
wiley   +1 more source

Synthetic CT‐enabled weekly adaptive radiotherapy for nasopharyngeal carcinoma: Optimizing plan adaptation triggers through volumetric–dosimetric monitoring

Journal of Applied Clinical Medical Physics, Volume 27, Issue 7, July 2026.
Abstract Background and purpose Anatomical changes during radiotherapy for nasopharyngeal carcinoma (NPC) frequently compromise target volume coverage while escalating dose delivery to organs at risk (OARs). In adaptive radiotherapy (ART), optimizing workflow efficiency to minimize clinical workload while maximizing patient benefit remains a ...
Zhenmei Cao, Chun Wu, Lixiang Han, Tingting Duan, Fengyu Zhang, Lansheng Zhang, Bin Wang, Weijie Lei, Xinye Ni   +8 more
wiley   +1 more source

Feasibility study: Use of an optical scanning system to obtain 3D body surface images suitable for total skin electron therapy treatment dosimetry

Journal of Applied Clinical Medical Physics, Volume 27, Issue 7, July 2026.
Abstract Background Total skin electron therapy (TSET, also known as TSE, TSI, TSEI or TSEBT) provides an effective treatment for extensive superficial lesions such as mycosis fungoides, although the standing setups and large distances used for treatment mean that comprehensive three‐dimensional (3D) dose calculations are rarely achievable clinically ...
Scott B. Crowe, Naasiha Cassim, Jenna Luscombe, Katie L. McMahon, Tanya Kairn   +4 more
wiley   +1 more source

Large-scale in vivo EPID dosimetry [PDF]

, 2017
Radiotherapy is a powerful method for treating cancer. It is also a very complex method, requiring many different systems and advanced machines to cooperate seamlessly.
Rozendaal, R.A.
core   +2 more sources

An integrated toolkit for structure generation, optimization, and evaluation in spatially fractionated radiation therapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 7, July 2026.
Abstract Purpose Spatially fractionated radiation therapy (SFRT) planning requires three coordinated tasks: generation of high‐dose sphere structures, position‐aware optimization, and peak‐valley dose ratio evaluation. In practice, clinicians and researchers address these tasks with a combination of closed‐source scripts, research codes, and manual ...
Japan K. Patel, Anthony Magliari, Gregory Gill, Todd A. Wareing, Tenzin Kunkyab, Caleb Raman, Ilias Sachpazidis, Peter Szentivanyi, Ryan Clark, Pierre Lansonneur, Arjun Karnwal, Michael Kudla, Sergejs Unterkirhers, Junqi Song, Jun Yang, Matthew C. Schmidt   +15 more
wiley   +1 more source

Measurement-based Monte Carlo dose calculation system for IMRT pretreatment and on-line transit dose verifications [PDF]

, 2009
[[abstract]]©2009 AIP - The aim of this study was to develop a dose simulation system based on portal dosimetry measurements and the BEAM Monte Carlo code for intensity-modulated (IM) radiotherapy dose verification.
Lin MH;Chao TC;Lee CC;Tung CJ;Yeh CY;Hong JH
core  

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 43-54, July 2026.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Development and characterization of a novel, small animal external beam irradiator using a clinical high dose rate brachytherapy source

Medical Physics, Volume 53, Issue 7, July 2026.
Abstract Background Pre‐clinical in vivo characterization is a necessary step in the translation of novel radiotherapeutic interventions to clinical application. In vivo irradiations using a radioactive source like Ir‐192 are challenging due to steep dose gradients and absence of universally available applicators that do not require physical contact or
Daniel Cecchi, Sacha Freeman, Greg Warren, Brad Gill, Chris Johnstone, Devika B. Chithrani, Samantha A. M. Lloyd   +6 more
wiley   +1 more source

Large-scale in vivo EPID dosimetry [PDF]

, 2017
Radiotherapy is a powerful method for treating cancer. It is also a very complex method, requiring many different systems and advanced machines to cooperate seamlessly.
Rozendaal, R.A.
core