Results 51 to 60 of about 120,987 (267)
Dynamic swallowing study for globus patients
World Journal of Otorhinolaryngology-Head and Neck Surgery, 2016 Objective: To examine whether pharyngeal swallowing function is impaired in globus patients with swallowing difficulty by dynamic swallowing study. Methods: Dynamic swallowing studies were performed on 80 normal adult volunteers and 33 globus patients ...
Jinrang Li +4 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
MULTIDISCIPLINARY APPROACH TO CHRONIC CONSTIPATION ASSOCIATED WITH FECAL INCONTINENCE IN CHILDREN [PDF]
Romanian Journal of Pediatrics, 2015 Constipation is a common symptom in clinical practice. Defi nition include abnormal transit diffi culty during defecation and abnormal stool consistency.
Claudia Olaru +8 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Functional distance in human gait transition
Acta Psychologica, 2015 The emerging understanding of the behavioral transitions that accompany the ascending and descending method of limits is in terms of "functional distance" - the degree to which a perceiver is disengaged from ordinary exploratory activities. Increasing functional distance results in negative hysteresis in contrast to the classical positive hysteresis ...
Mohammad Abdolvahab, Claudia Carello
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Regulation of PDGFRα+ cells and ICC in progesterone-mediated slow colon transit in pregnant mice
HeliyonBackground: Progesterone can inhibit intestinal smooth muscle contraction; however, the specific mechanism remains unclear. Besides smooth muscle cells, smooth muscle has two important mesenchymal cells, namely interstitial cells of Cajal (ICC) and ...
Chen Lu +7 more
doaj +1 more source
Development of Urban Service Function of Multi-level Rail Transit in Cities (Clusters) [PDF]
中国工程科学Currently, with the in-depth promotion of new urbanization and regional coordinated development strategies, megacities (clusters) with strong driving capabilities have emerged in China, posing urgent demands for building a multi-level rail transit system
Guizhong Zhang +3 more
doaj +1 more source
Between Pricing and Investment, What Mobility Policies Would Be Advantageous for Île-de-France?
Journal of Advanced Transportation, 2020 This article provides a prospective study of mobility policies for the private car and public transit (PT) modes of transportation in the Paris Ile-de-France region. Different economic instruments are considered: pricing of car traffic or transit service,
Fabien Leurent, Sheng Li
doaj +1 more source