Results 61 to 70 of about 120,987 (267)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Population Aggregation Effect of Urban Rail Transit Stations in Chengdu and Other Megacities Behemoths

Chengshi guidao jiaotong yanjiu
ObjectiveMegacities behemoths generally face transformation and development requirements such as controlling the total population and guiding a rational distribution of population.
Yuan JIANG, Na ZHANG, Yin ZHOU, Xiaorong ZHANG, Xiaonian SHAN   +4 more
doaj   +1 more source

Regular Transition Functions and Regular Superprocesses [PDF]

Transactions of the American Mathematical Society, 1989
The class of regular Markov processes is very close to the class of right processes studied by Meyer, Getoor and others. We say that a transition function p p is regular if it is the transition function of a well-defined regular Markov process. A characterization of regular transition functions is given which implies that, if
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Hot Jupiters around M dwarfs

EPJ Web of Conferences, 2013
The WFCAM Transit Survey (WTS) is a near-infrared transit survey running on the United Kingdom Infrared Telescope (UKIRT). We conduct Monte Carlo transit injection and detection simulations for short period (
Murgas F., Martín E., Koppenhoefer J., Cruz P., Cappetta M., Birkby J., Barrado D., Pinfield D., Sipőcz B., Hodgkin S., Kovács Gábor, Nefs B., Saglia R., Zendejas J.   +13 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Evolution Characteristics and Implications of Seoul Metropolitan Area Rail Transit

Chengshi guidao jiaotong yanjiu
Objective The comprehensive understanding of rail transit evolution in developed metropolitan areas abroad is beneficial for the scientific construction of rail transit network and the rational scheduling of construction phases in China′s mega and super ...
ZHOU Na, WANG Chaoshen
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Column continuous transition functions

Journal of Mathematical Analysis and Applications, 2007
The author considers \(\mathbb{Z}^{+}\)-valued continuous-time Markov chains with column continuous transition functions. A transition function \(P(t) =(P_{ij}^{(t)})_{i,j\in \mathbb{Z}^{+}},\) \(t\geq 0\), is said to be column continuous if \(\lim_{t\rightarrow 0}P_{ij}(t) =\delta _{ij}\) uniformly in \(i\in \mathbb{Z}^{+}\) for any \(j\in \mathbb{Z}^{
openaire   +2 more sources