Results 81 to 90 of about 120,987 (267)

Revealing job accessibility supported by public transit services using a graph convolutional network

open access: yesGeo-spatial Information Science
Encouraging the use of public transit is widely recognized as a viable solution to address urban transportation issues such as increasing congestion and pollution.
Meihan Jin   +4 more
doaj   +1 more source

Rotational Representations of Transition Matrix Functions

open access: yesThe Annals of Probability, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analysis on Computer Interlocking Logic Design for Main Line of Urban Rail Transit

open access: yes机车电传动, 2012
Function of computer interlocking equipment, which was considered as one of core subsystem of signal system was discussed. Moreover, in terms of practical requirement, a modified method of interlocking logic realization was proposed.
LIANG Yun-peng, WANG Cheng, LV Hao-jiong
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Nonparametric Estimation of Markov Transition Functions

open access: yesThe Annals of Statistics, 1979
Let $\{X_n\}$ be a Markov chain having a stationary transition function and assume that the state set is an arbitrary set in a Euclidean space. The state transition law of the chain is given by a function $F(y|x) = P\lbrack X_{n+1} \leqslant y|X_n = x\rbrack$, which is assumed defined and continuous for all $x$.
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Systematic Review of the Coopetition Relationship between Bike-Sharing and Public Transit

open access: yesJournal of Advanced Transportation
The sharing economy, mobile Internet, and smartphones have been widely utilized in recent years to promote the development of bike-sharing services. Bike-sharing serves as a first/last mile travel mode to connect to public transit, which improves trip ...
Jianhong Ye, Jiahao Bai, WenYang Hao
doaj   +1 more source

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