Results 91 to 100 of about 1,148 (222)

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source

Aridity and grazing are associated with reduced trait complementarity and higher invasion intensity of Solanum rostratum in native plant communities

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The biotic resistance hypothesis (BRH) of Elton posits that diverse communities are more resistant to biological invasions. While the effects of climatic stresses and human disturbances on community invasibility have been extensively studied individually, their combined
Kai Shi, Misbah Naz, Chi Zhang, Hua Shao
wiley   +1 more source

OrCAS: Origins, Compositions, and Atmospheres of Sub-Neptunes. I. Survey Definition

The Astronomical Journal
Sub-Neptunes—volatile-rich exoplanets smaller than Neptune—are intrinsically the most common type of planet known. However, the formation and nature of these objects, as well as the distinctions between subclasses (if any), remain unclear.
Ian J. M. Crossfield, Alex S. Polanski, Paul Robertson, Joseph Akana Murphy, Emma V. Turtelboom, Rafael Luque, Thomas Beatty, Tansu Daylan, Howard Isaacson, Jonathan Brande, Laura Kreidberg, Natalie M. Batalha, Daniel Huber, Maleah Rhem, Courtney Dressing, Stephen R. Kane, Malik Bossett, Anna Gagnebin, Maxwell A. Kroft, Pranav H. Premnath, Claire J. Rogers, Karen A. Collins, David W. Latham, Cristilyn N. Watkins, David R. Ciardi, Steve B. Howell, Arjun B. Savel, Perry Berlind, Michael L. Calkins, Gilbert A. Esquerdo, Jessica Mink, Catherine A. Clark, Michael B. Lund, Rachel A. Matson, Mark E. Everett, Joshua E. Schlieder, Elisabeth C. Matthews, Steven Giacalone, Thomas Barclay, Roberto Zambelli, Peter Plavchan, Taylor Ellingson, Michael Bowen, Gregor Srdoc, Kim K. McLeod, Richard P. Schwarz, Khalid Barkaoui, Jacob Kamler, Felipe Murgas, Enric Palle, Norio Narita, Akihiko Fukui, Howard M. Relles, Allyson Bieryla, Eric Girardin, Bob Massey, Chris Stockdale, Pablo Lewin, Riccardo Papini, Pere Guerra, Dennis M. Conti, Selçuk Yalçinkaya, Özgür Baştürk, Ghachoui Mourad   +63 more
doaj   +1 more source

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

Determination of Reference Intervals for Selected Liver Biomarkers With Focus on Pre‐ and Postanalytical Factors in Lactating Dairy Cattle

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Measurement of liver enzymes and metabolites for both clinically healthy and sick cattle is a routine part of dairy herd management. Reference intervals (RIs) are influenced by many variables, including pregnancy, breeding, and geographical variables, and can shift over time.
Anna Theile, Merle Hardekopf, Marion Schmicke   +2 more
wiley   +1 more source

Reference Intervals of Selected Serum and Plasma Biochemical Analytes in Clinically Healthy Multiparous Holstein Cows During the Periparturient Period

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Monitoring the metabolic changes during the periparturient period is crucial. Objective We aimed to establish reference intervals (RIs) of several serum and plasma biochemical variables in multiparous periparturient Holstein dairy cows. Methods A total of 238 multiparous dry cows from six commercial dairy farms were enrolled.
Nektarios Siachos, Georgios Oikonomou, Nikolaos Panousis, Ioannis Sampsonidis, Stavros Kalogiannis, Georgios Arsenos, Georgios E. Valergakis   +6 more
wiley   +1 more source

Status of the Calan-Hertfordshire Extrasolar Planet Search

EPJ Web of Conferences, 2013
In these proceedings we give a status update of the Calan-Hertfordshire Extrasolar Planet Search, an international collaboration led from Chile that aims to discover more planets around super metal-rich and Sun-like stars, and then follow these up with ...
Jordán Andres, Ivanyuk Oleksiy, Pavlenko Yakiv, Barnes John R., Jones Matias I., Murgas Felipe, Tuomi Mikko, Rojo Patricio, Jenkins James S., Jones Hugh R.A., Day-Jones Avril C., Ruiz Maria-Teresa, Pinfield David J.   +12 more
doaj   +1 more source

Reduced osmoresponsiveness in magnocellular neuroendocrine neurones during chronic salt‐loading

The Journal of Physiology, EarlyView.
Abstract figure legend We conducted a large systematic survey of the physiological and electrophysiological characteristics of the magnocellular neurosecretory neurones of the supraoptic nucleus in euhydrated and salt‐loaded conditions. Our in vivo electrophysiological recordings show that, after 7 days of salt‐loading, the neuronal responsiveness to ...
Maja Lozic, Roongrit Klinjampa, Nancy Sabatier, Duncan J. MacGregor, Gareth Leng, Mike Ludwig   +5 more
wiley   +1 more source

Conformational Rearrangement of Fission DSPs

BioEssays, Volume 47, Issue 11, November 2025.
Assembly properties of fission DSPs. Fission DSPs exist in a dynamic equilibrium of oligomer states in the cytosol, where they must be activated by partner proteins or lipid to induce assembly, and upon GTP hydrolysis, constriction. ABSTRACT Dynamin superfamily proteins (DSPs) are large GTPases that play crucial roles in membrane remodeling processes ...
Anelise N. Hutson, Kristy Rochon, Jason A. Mears   +2 more
wiley   +1 more source

Dazzle: Oversampled Image Reconstruction and Difference-imaging Photometry for the Nancy Grace Roman Space Telescope

The Astronomical Journal
We present algorithms and software for constructing high-precision difference images to detect and measure transients, such as microlensing events, in crowded stellar fields using the Nancy Grace Roman Space Telescope.
Michael D. Albrow
doaj   +1 more source