Results 91 to 100 of about 968 (198)

Dazzle: Oversampled Image Reconstruction and Difference-imaging Photometry for the Nancy Grace Roman Space Telescope

The Astronomical Journal
We present algorithms and software for constructing high-precision difference images to detect and measure transients, such as microlensing events, in crowded stellar fields using the Nancy Grace Roman Space Telescope.
Michael D. Albrow
doaj   +1 more source

Evaluation of High‐Density Lipoprotein Capacity to Acquire Free Cholesterol From Triglyceride‐Rich Lipoproteins During Reverse Remnant‐Cholesterol Transport in Familial Hypercholesterolemia

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
In familial hypercholesterolemia, HDL's absolute capacity to acquire free cholesterol from triglyceride‐rich lipoproteins during lipolysis is preserved, yet normalized HDL function indices relative to LDL‐C and non‐HDL‐C are markedly reduced in homozygous patients, suggesting these ratios as potential biomarkers for identifying high‐risk phenotypes ...
Shiva Ganjali, Judy B. de Haan, Wilfried Le Goff, Anatol Kontush, Amirhossein Sahebkar   +4 more
wiley   +1 more source

An Oasis in the Brown Dwarf Desert: Confirmation of Two Low-mass Transiting Brown Dwarfs Discovered by TESS

The Astronomical Journal
As the intermediate-mass siblings of stars and planets, brown dwarfs (BDs) are vital to study for a better understanding of how objects change across the planet-to-star mass range.
Elina Yuchen Zhang, Theron W. Carmichael, Daniel Huber, Keivan G. Stassun, Akihiko Fukui, Norio Narita, Felipe Murgas, Enric Palle, David W. Latham, Michael L. Calkins, Sara Seager, Joshua N. Winn, Michael Vezie, Rebekah Hounsell, Hugh P. Osborn, Douglas A. Caldwell, Jon M. Jenkins   +16 more
doaj   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Searching for GEMS: Discovery and Characterization of Two Brown Dwarfs Around M Dwarfs

The Astronomical Journal
Brown dwarfs bridge the gap between stars and planets, providing valuable insight into both planetary and stellar-formation mechanisms. Yet the census of transiting brown-dwarf companions, in particular around M-dwarf stars, remains incomplete. We report
Alexander Larsen, Tera N. Swaby, Henry A. Kobulnicky, Caleb I. Cañas, Shubham Kanodia, Jessica Libby-Roberts, Andrew Monson, Arvind F. Gupta, William Cochran, Suvrath Mahadevan, Chad Bender, Scott A. Diddams, Samuel Halverson, Andrea S. J. Lin, Maxwell Moe, Joe Ninan, Paul Robertson, Arpita Roy, Christian Schwab, Gudmundur Stefansson   +19 more
doaj   +1 more source

Constraining exotrojans in hot-Jupiter systems using transit timing variation observations from TESS

Astronomy & Astrophysics
Context. Co-orbital objects, also known as Trojans, are celestial bodies that share a 1:1 mean motion resonance orbit with a planet. Many planets in our Solar System hold Trojans, yet none has been confirmed in exoplanetary systems.
Zhang Zixin, Wang Wenqin, Ma Xinyue, Chen Zhangliang, Wang Yonghao, Yu Cong, Liu Shangfei, Gao Yang, Tang Baitian, Chen Dichang, Ma Bo   +10 more
doaj   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

MedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu, Xinyan Wu, Ting Yin, Feining Huang, Manqi Kong, Yu Yang, Zinan Liu, Jiabin Yu, Tianpeng Zhang   +8 more
wiley   +1 more source

The HD 60779 Planetary System: A Transiting Sub-Neptune on a 30 Day Orbit and a More Massive Outer World

The Astronomical Journal
We present the discovery of the planetary system orbiting the bright ( V = 7.2), nearby (35 pc), Sun-like ( M _⋆  = 1.050 ± 0.044 M _⊙ , R _⋆  = 1.129 ± 0.013 R _⊙ ) star, HD 60779.
Victoria DiTomasso, David Charbonneau, Andrew Vanderburg, Mercedes López-Morales, Shreyas Vissapragada, Annelies Mortier, Thomas G. Wilson, Elyse Incha, Andrew Collier Cameron, Luca Malavolta, Lars A. Buchhave, David W. Latham, Matteo Pinamonti, Stephanie Striegel, Michael Fausnaugh, Luke Bouma, Ben Falk, Robert Aloisi, Xavier Dumusque, A. Anna John, Ben S. Lakeland, A. F. Martínez Fiorenzano, Luca Naponiello, Belinda Nicholson, Emily K. Pass, Francesco Alfonso Pepe, Federica Rescigno, Alessandro Sozzetti, Daisy A. Turner, Saul A. Rappaport, Mark Omohundro, Brian P. Powell, Robert Gagliano, Thomas L. Jacobs, Veselin B. Kostov, Martti H. Kristiansen, Daryll M. LaCourse, Allan R. Schmitt, Hans Martin Schwengeler, Ivan A. Terentev   +39 more
doaj   +1 more source

Dexmedetomidine Rapidly Relieves Stress‐Induced Hyperalgesia via Presynaptic α2‐Adrenergic Inhibition at Orbitofrontal–Insular Glutamatergic Synapses

MedComm, Volume 7, Issue 7, July 2026.
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong, Yang‐Xun Zhang, Huijie Zhu, Yinyao Li, Yunfan Hou, Yun‐Yong Xie, Lu‐Yao Li, Bei‐Bei Zhang, Shu‐Tao Xie, Wei Zhang, Qi‐Peng Zhang, Xiao‐Yang Zhang, Jing‐Ning Zhu, Xiaoping Gu, Zhengliang Ma   +14 more
wiley   +1 more source

Understanding cation exchange capacity through the landscape lens of the Busoga Catena, Uganda

Soil Science Society of America Journal, Volume 90, Issue 4, July/August 2026.
Abstract This study identifies the parent material (PM) and examines cation exchange capacity (CEC) across the Busoga catena. In 2022 and 2023, we described 32 pedons and collected 147 samples. Laboratory analyses were particle size analysis, organic carbon (OC) content, pH, and CEC.
Rebecca Alice Wokibula, Francis Akitwine, Johnson Godlove Mtama, Moureen Mbeiza, Richard C. Schultz, Richard M. Cruse, Andrew K. Manu, David G. Acker, C. Lee Burras   +8 more
wiley   +1 more source