Results 61 to 70 of about 274,344 (248)

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu   +17 more
wiley   +1 more source

Validating the Orbital Periods of the Coolest TESS Planet Candidates

open access: yesThe Astronomical Journal
When an exoplanet passes in front of its host star, the resulting eclipse causes an observable decrease in stellar flux, and when multiple such transits are detected, the orbital period of the exoplanet can be determined. Over the past seven years NASA’s
Dillon J. Bass, Daniel C. Fabrycky
doaj   +1 more source

Optimized transit detection algorithm to search for periodic transits of small planets [PDF]

open access: yesAstronomy & Astrophysics, 2019
We present a new method to detect planetary transits from time-series photometry, the transit least squares (TLS) algorithm. TLS searches for transit-like features while taking the stellar limb darkening and planetary ingress and egress into account.
M. Hippke, R. Heller
semanticscholar   +1 more source

Comet C/2011 J2 (LINEAR): Photometry and stellar transit [PDF]

open access: yesPlanetary and Space Science, 2016
We present results of two-year photometric monitoring of Comet C/2011 J2 (LINEAR) that spans the time period from February 2013 through December 2014, before and after perihelion passage. The observations were conducted with broadband R filter. Analysis of observations of Comet C/2011 J2 (LINEAR) allows estimating the nucleus radius as function of ...
Ivanova, Oleksandr   +6 more
openaire   +2 more sources

Cortico‐Striatal‐Midbrain Circuit Dysregulation Underlying MK‐801 Induced Impulsivity and the Ameliorative Effects of SEP

open access: yesAdvanced Science, EarlyView.
Impulsivity is a symptom across multiple psychiatric disorders, yet its neural basis remains elusive. This study shows that the NMDAR antagonist MK‐801 elevates dopamine release and disrupts neuronal selectivity in the nucleus accumbens, leading to impulsive behavior.
Xueru Wang   +6 more
wiley   +1 more source

Transiting Planetary Debris near the Roche Limit of a White Dwarf on a 4.97 hr Orbit—and its Vanishing

open access: yesThe Astrophysical Journal
We present the discovery of deep, irregular, periodic transits toward the white dwarf ZTF J1944+4557 using follow-up time-series photometry and spectroscopy from Palomar, Keck, McDonald, Perkins, and Lowell observatories.
Joseph A. Guidry   +11 more
doaj   +1 more source

Photometry and transit modelling of exoplanet WASP-140b

open access: yes, 2022
Accepted by JAAVSO, 12 pages, 5 figures, 2 ...
North, Allen, Banks, Timothy
openaire   +2 more sources

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

open access: yesAdvanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li   +13 more
wiley   +1 more source

TESS Timings of 31 Hot Jupiters with Ephemeris Uncertainties

open access: yesThe Astrophysical Journal Supplement Series, 2023
A precise transit ephemeris serves as the premise for follow-up exoplanet observations. We compare TESS Object of Interest (TOI) transit timings of 262 hot Jupiters with the archival ephemeris and find 31 of them having TOI timing offsets, among which ...
Su-Su Shan   +10 more
doaj   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy