Results 61 to 70 of about 242,108 (213)

Detecting false positives with PLATO using double-aperture photometry and centroid shifts

Astronomy & Astrophysics
Context. PLATO will discover exoplanets and characterize their host stars. Since photometry for most PLATO targets will be extracted on board, an efficient strategy to detect false positives (FPs) – transit-like signals not caused by planets – is needed.
Gutiérrez-Canales F., Samadi R., Birch A., Cabrera J., Damiani C., Guterman P., Paproth C., Pertenais M., Santerne A.   +8 more
doaj   +1 more source

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

Advanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel, Soumik Ray, Federica Saraceno, Giacomo Nisini, Georgia Nasi, Thomas Oliver Mason, Antonin Kunka, Effrosyni Agrimaki, Dannie Juul Olesen, Francesco Simone Ruggeri, Alexander K. Buell   +10 more
wiley   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source

Updated Masses for the Gas Giants in the Eight-planet Kepler-90 System Via Transit-timing Variation and Radial Velocity Observations

The Astronomical Journal
The eight-planet Kepler-90 system exhibits the greatest multiplicity of planets found to date. All eight planets are transiting and were discovered in photometry from the NASA Kepler primary mission. The two outermost planets, g ( P _g  = 211 days) and h
David E. Shaw, Lauren M. Weiss, Eric Agol, Karen A. Collins, Khalid Barkaoui, Cristilyn N. Watkins, Richard P. Schwarz, Howard M. Relles, Chris Stockdale, John F. Kielkopf, Fabian Rodriguez Frustaglia, Allyson Bieryla, Joao Gregorio, Owen Mitchem, Katherine Linnenkohl, Adam Popowicz, Norio Narita, Akihiko Fukui, Michaël Gillon, Ramotholo Sefako, Avi Shporer, Adam Lark, Amelie Heying, Isa Khan, Beibei Chen, Kylee Carden, Donald M. Terndrup, Robert Taylor, Dasha Crocker, Sarah Ballard, Daniel C. Fabrycky   +30 more
doaj   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

TOD203: Transit Corridors and TOD

, 2010
This guidebook illustrates how planning at the corridor scale can help transit investments capture the benefits of TOD, said Sam Zimbabwe, director of the Center for Transit-Oriented Development.
The Center for Transit-Oriented Development
core   +2 more sources

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Sporadic Dips from Extended Debris Transiting the Metal-rich White Dwarf SBSS 1232+563

The Astrophysical Journal
We present the discovery of deep but sporadic transits in the flux of SBSS 1232+563, a metal-rich white dwarf polluted by disrupted exoplanetary debris.
J. J. Hermes, Joseph A. Guidry, Zachary P. Vanderbosch, Mariona Badenas-Agusti, Siyi Xu, Malia L. Kao, Antonio C. Rodriguez, Keith Hawkins   +7 more
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

A transit timing analysis with combined ground- and space-based photometry

EPJ Web of Conferences, 2015
The analysis of timing variations of transiting exoplanets allows one to discover additional planets in the system. Such bodies can be very low in mass and radius, so that they remain undetected by transit or radial velocity methods.
Raetz St., Fernandez M., Marka C., Heras A. M., Maciejewski G.   +4 more
doaj   +1 more source