Results 231 to 240 of about 9,228,850 (295)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Interpreting Left Atrial Contrast Dynamics in Atrial Fibrillation: Rhythm Status, Hemodynamic Confounders, and Clinical Generalizability. [PDF]

Korean J Radiol
Mi HX, Zhang P.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Beyond a universal obesity microbiome signature: pre-intervention heterogeneity and a framework for baseline profiling. [PDF]

Front Nutr
Liu P, Mao R, Li N, Guo J, Wang J, Mao J.   +5 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Association between GLP-1-based therapy and small-bowel transit time during capsule endoscopy: a prospective, multicentre, observational study. [PDF]

BMJ Open Gastroenterol
Baker FA, Melhem M, Kalnizki O, Khader M, Dardik M, Tatour M, Hazzan R.   +6 more
europepmc   +1 more source

P2X7R+CD8αβ⁺ T cells exacerbate postoperative ileus by inducing the loss of enterochromaffin cells. [PDF]

iScience
Bu F, Huang S, Yang X, Wei L, Yang Y, Zhang Z, Zhang D, Tian D.   +7 more
europepmc   +1 more source