Results 171 to 180 of about 14,727,172 (294)

Research progress on prehospital delay of aortic dissection patients

Huli yanjiu, 2020
XIAO Yaru, HUANG Sufang, ZOU Dengxiu, ZHENG Danli   +3 more
doaj  

Unlocking the colon clock: Bridging the gap in colonic transit time studies for optimal management of chronic constipation. [PDF]

World J Gastrointest Pharmacol Ther
Kalra S, Goyal MK, Goyal K, Singh R, Vuthaluru AR, Goyal O.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Alterations in Oral Cecal Transit Time and Small Intestinal Microbiota in Minimal Hepatic Encephalopathy With Small Intestinal Bacterial Overgrowth. [PDF]

Clin Transl Gastroenterol
Cao L, Meng Y, Huang Y, Ye H, Han C, Liu X, Wu Y, Song Y, Wang Z, Cong Y, Wang L, Wang W, Wang Y, Zhao K, Wei H, Ren K, Mao Q, Cui M, Wang J, Cao B.   +19 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Quantifying capillary transit time distribution: a novel tracer kinetic model accounting for leakiness, back diffusion, and perfusion in MRI and PET imaging-the outflow model. [PDF]

EJNMMI Phys
Larsson HBW, Cramer SP, Tireli ED, Larsson TSW, Lindberg U, Vestergaard MB.   +5 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Monitoring sympathectomy in regional anesthesia: pulse wave transit time variability after interscalene block. [PDF]

Korean J Anesthesiol
Song JW.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Bowel Transit Time May Be Accelerated in Colonic Diverticulosis Independent of Mucosal Serotonin Signaling. [PDF]

J Clin Med
Nehring P, Jastrzębski M, Joniec-Maciejak I, Wawer A, Przybyłkowski A.   +4 more
europepmc   +1 more source