Results 41 to 50 of about 14,727,172 (294)
D+ (high digestion efficiency) and D− (low digestion efficiency) genetic chicken lines selected for divergent digestion efficiency were compared in this experiment.
N. Rougière, B. Carré
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Groundwater transit time distributions (TTDs) describe the spectrum of flow‐weighted apparent ages of groundwater from aquifer recharge to discharge.
C. Eric Humphrey +8 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Background Transit time is an important modulator of the human gut microbiome. The inability to modify transit time as the sole variable hampers mechanistic in vivo microbiome research.
Yorick Minnebo +5 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The fluorescence index called the Transit Time index (TTi) is based on the fluorescence of natural organic matter in order to qualitatively assess the transit time of karst groundwater, using springs affected by human activities.
Leïla Serène +7 more
doaj +1 more source
Passage performance of brown trout (Salmo trutta), Iberian barbel (Luciobarbus bocagei), and northern straight-mouth nase (Pseudochondrostoma duriense) was investigated in a vertical slot fishway in the Porma River ...
Sanz-Ronda F.J. +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A novel dual-band nested transit time oscillator
A novel dual-band nested transit time oscillator (TTO) is proposed in this paper, which consists of an outer X-band coaxial TTO and an inner Ka-band coaxial TTO.
Xingfu Gao +6 more
doaj +1 more source

