Results 111 to 120 of about 8,161,910 (315)

Sideband Transitions and Two-Tone Spectroscopy of a Superconducting Qubit Strongly Coupled to an On-Chip Cavity [PDF]

, 2007
Andreas Wallraff, David Schuster, Alexandre Blais, Jay Gambetta, J. A. Schreier, Luigi Frunzio, Michel Devoret, S. M. Girvin, Robert Schoelkopf   +8 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Prediction of fire danger index using a new machine learning based method to enhance power system resiliency against wildfires

IET Generation, Transmission & Distribution
Wildfires, which can cause significant damage to power systems, are mostly inevitable and unpredictable. Fire danger indexes, such as the Forest Fire Danger Index (FFDI) and the Canadian Fire Weather Index (FWI), measure the potential wildfire danger at ...
Tan Nhat Pham, Rakibuzzaman Shah, Nima Amjady, Syed Islam   +3 more
doaj   +1 more source

A 3D Numerical Model to Estimate Lightning Types for PyroCb Thundercloud

Applied Sciences
Pyrocumulonimbus (pyroCb) thunderclouds, produced from extreme bushfires, can initiate frequent cloud-to-ground (CG) lightning strikes containing extended continuing currents.
Surajit Das Barman, Rakibuzzaman Shah, Syed Islam, Apurv Kumar   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Australian fire weather variability using calibrated long-term reanalysis data

Discover Environment
Spatiotemporal variability on multi-decadal time scales can be observed in weather conditions associated with wildfires. The climatic factors that drive this variability in fire weather conditions have been studied using bias-corrected 20th Century ...
Soubhik Biswas, Savin S. Chand, Andrew J. Dowdy, Krishneel Sharma   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Hepatic Lipid Metabolism in Transition Dairy Cows Fed Flaxseed [PDF]

, 2007
H.V. Petit, Marie‐France Palin, L. Doepel   +2 more
openalex   +1 more source