Results 161 to 170 of about 3,224,146 (301)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The UME-to-GME Transition Toolkit: Guidance for Stakeholders Across Medical Education. [PDF]
J Grad Med EducSheets ZC +12 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Coal regions are particularly vulnerable to the plans to reduce regional pollution and move towards a climate-neutral economy. The European Union therefore supports the transition away from coal in those regions that are socio-economically most affected ...
Eichhammer, Wolfgang +2 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Banking in transition countries [PDF]
Modern banking institutions were virtually non-existent in the planned economies of central Europe and the former Soviet Union. In the early transition period, banking sectors began to develop during several years of macroeconomic decline and turbulence ...
Hasan, Iftekhar +2 more
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An international observational study on transition of care from paediatric to adult services for patients with mucopolysaccharidosis II. [PDF]
BMC Health Serv ResStepien KM +10 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Building a bridge : a resource manual for high school students
, 2009 Rev. 2009.; Title from PDF t.p.(publisher's Web site, viewed July 23, 2010).; "This manual was originally developed in 1991 through the Connecticut Parent Advocacy Center by Jan Hine in collaboration with the Parent-Student Subcommittee of the ...
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