Results 231 to 240 of about 7,434,848 (282)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Deprotonation-controlled copper-free Pd-catalyzed Sonogashira coupling <i>versus</i> the Kumada-Tamao-Corriu reaction: a DFT investigation toward anticancer carborane alkynes. [PDF]

RSC Adv
Soltani E, Bayat M.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Bullying Profiles and Co-Rumination: A Latent Transition Analysis in Adolescents. [PDF]

Aggress Behav
Misas M, Camacho A, Romera EM.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Lattice softening and diffusive dynamics in the polar metal LiReO₃. [PDF]

Sci Adv
Murayama K, Masuki R, Tassel C, Sakai H, Yanagisawa T, Yoshida K, Oike H, Yoshida S, Gu X, Ishida K, Namba M, Denisova K, Dupray V, Clevers S, Mentré O, Nomoto T, Tadano T, Brown CM, Lemmens P, Arita R, Takatsu H, Kageyama H.   +21 more
europepmc   +1 more source

The experience of newly qualified nurses one year after prematurely transitioning to the professional world during the Covid-19 pandemic in Spain. [PDF]

BMC Nurs
Rodríguez-Monforte M, Rifà-Ros R, Escrig-Piñol A, Reyes-Vizcarro M, Carrillo-Álvarez E, Berlanga-Fernández S, Amorós-Molina Á, Martín-Arribas A.   +7 more
europepmc   +1 more source