Results 91 to 100 of about 2,405,636 (294)

Double Beta Decay, Nuclear Structure and Physics beyond the Standard Model

, 2011
Neutrinoless Double Beta Decay ($0\nu\beta\beta$) is presently the only known experiment to distinguisch between Dirac neutrinos, different from their antiparticles, and Majorana neutrinos, identical with their antiparticles. In addition $0\nu\beta\beta$
Amand Faessler, Escuderos A, Faessler A, Kortelainen M, Rodin V A, Rodriguez T R   +5 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Critical Materials: A Changing Horizon

CHIMIA
New and emerging technologies impact on the global demand for raw materials, and 30–40 minerals/materials are classed as ‘critical’.
Catherine E. Housecroft
doaj   +1 more source

Resveratrol Protects against Cerebral Ischemic Injury via Restraining Lipid Peroxidation, Transition Elements, and Toxic Metal Levels, but Enhancing Anti-Oxidant Activity. [PDF]

Antioxidants (Basel), 2021
Lin MC, Liu CC, Lin YC, Liao CS.
europepmc   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Changing times: does the critical success factors boosting green transition of SMEs remain unchanged?

Journal of Innovation and Entrepreneurship
This study aims to conduct a thorough analysis to determine the key elements that contribute to the behavioral intention of small and medium enterprises (SMEs) to adopt green transition.
Pham Quang Huy, Vu Kien Phuc
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Modeling Transition Metals in East Asia and Japan and Its Emission Sources

GeoHealth, 2020
Emission inventories of anthropogenic transition metals, which contribute to aerosol oxidative potential (OP), in Asia (Δx = 0.25°, monthly, 2000–2008) and Japan (Δx = 2 km, hourly, mainly 2012) were developed, based on bottom‐up inventories of ...
Mizuo Kajino, Hiroyuki Hagino, Yuji Fujitani, Tazuko Morikawa, Tetsuo Fukui, Kazunari Onishi, Tomoaki Okuda, Tomoki Kajikawa, Yasuhito Igarashi   +8 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source