Results 191 to 200 of about 417,860 (267)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Mechanism-informed transition from pediatric to adult care in sickle cell disease: a case study. [PDF]

BMC Health Serv Res
Hankins JS, Aurora T, Matsumoto R, Malone S, Baumann AA.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Tuning the metal-support interactions in transition metal-anchored heteroatom-doped graphene single-atom catalysts.

Phys Chem Chem Phys
van Dam AN, Vermeeren P.
europepmc   +1 more source

An embodied cognition based model of medical experts' tacit knowledge: structure, hierarchies, and transformation. [PDF]

Front Digit Health
Zhou H, Chang X, Zhou X, Shi J, Zhou Z, Zhong S.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Experiences of Transition From Early-Intervention to Education-Based Therapy Services for Parents of Children With Physical Childhood-Onset Disabilities: A Scoping Review. [PDF]

Child Care Health Dev
Kidd S, Williams SA, Graham F.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Open questions on viral frameshifting: Exploiting the structural plasticity of the frameshifting element for therapeutic intervention. [PDF]

Biophys J
Portillo-Ledesma S, Lee S, Laederach A, Schlick T.   +3 more
europepmc   +1 more source

Genome-Wide Characterization and Transcriptional Profiling of the WRKY Gene Family During Heartwood Formation in <i>Dalbergia odorifera</i>. [PDF]

Genes (Basel)
Ma R, Xu Y, Liu H, Wei Q, Luo J, Liu B, Fu Y.   +6 more
europepmc   +1 more source