Results 271 to 280 of about 480,980 (318)
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Genetic Dissection of the Permeability Transition Pore
Journal of Bioenergetics and Biomembranes, 2005The permeability transition pore (PTP) regulates the structural re-organization of mitochondria in response to changes in cellular Ca(2+) and is thought to be an important participant in mitochondrial responses to cell death signals. Although the proteins forming the PTP have yet to be rigorously identified, recent examination of the response of ...
BERNARDI, PAOLO, FORTE M.
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Molecular genetic aspects of prostate transition zone lesions
Urology, 2003The prostate is a composite exocrine gland divided into four zones: anterior fibromuscular stroma, peripheral zone (PZ), central zone, and preprostatic tissue. The preprostatic tissue is the smallest, but most complex, prostate zone. Its main component is a cylindrical, smooth, muscular sphincter. Inside this muscle, are tiny periurethral glands.
Jasminka, Pavelić +2 more
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Genetic algorithm based transition probabilities estimation
2017 13th IEEE Conference on Automation Science and Engineering (CASE), 2017Renal transplantation is the best treatment for end-stage renal disease. Transplanted patients need to take immunosuppressant drugs to keep long-term survival. However, the cost of immunosuppressant drugs is high in China, so it is necessary to conduct a cost-effectiveness analysis of immunosuppressant drugs to provide guidance for medical decision ...
Xiuxian Wang +3 more
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Genetically transitional disease: a new concept in genomic medicine
Trends in Genetics, 2023Traditional classification of genetic diseases as monogenic and polygenic has lagged far behind scientific progress. In this opinion article, we propose and define a new terminology, genetically transitional disease (GTD), referring to cases where a large-effect mutation is necessary, but not sufficient, to cause disease.
Qingping Yao +3 more
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Urology, 1999
Multifocality of transitional cell carcinoma (TCC) has been attributed to seeding of exfoliated tumor cells or to a general sensitivity of the entire urothelium to carcinogenic stimuli. By contrast, TCC has been shown to evolve as a consequence of genetic defects and chromosomal instability.
A, Pycha +6 more
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Multifocality of transitional cell carcinoma (TCC) has been attributed to seeding of exfoliated tumor cells or to a general sensitivity of the entire urothelium to carcinogenic stimuli. By contrast, TCC has been shown to evolve as a consequence of genetic defects and chromosomal instability.
A, Pycha +6 more
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Simulating economic transition processes by genetic programming
Annals of Operations Research, 2000zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chen, Shu-Heng, Yeh, Chia-Hsuan
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Imaging and Genetic Biomarkers Predicting Transition to Psychosis
2018The search for diagnostic and prognostic biomarkers in schizophrenia care and treatment is the focus of many within the research community. Longitudinal cohorts of patients presenting at elevated genetic and clinical risk have provided a wealth of data that has informed our understanding of the development of schizophrenia and related psychotic ...
Stuart A, Hunter, Stephen M, Lawrie
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Phase Transitions in Genetic Programming Search
2007Phase transitions occur in computational, as well as thermodynamic systems. Of particular interest is the possibility that phase transitions occur as a consequence of GP search. If this were so, it would allow for a statistical mechanics approach and quantitative comparisons of GP with a broad variety of rigorously described systems.
Jason M. Daida +3 more
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Evolutionary transition on Virus-Evolutionary Genetic Algorithm
Proceedings of 1997 IEEE International Conference on Evolutionary Computation (ICEC '97), 2002The paper deals with a genetic algorithm (GA) based on the virus theory of evolution (VEGA) and evolutionary transition of a population. VEGA can self adaptively change the searching ratio between local search and global search according to the current state of population of candidate solutions.
N. Kubota +3 more
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“Biomarking” the transition from genetic risk to kidney disease
Kidney International, 2018Only some individuals carrying the high-risk APOL1 genotype go on to develop kidney disease phenotypes. In this issue of Kidney International, Nadkarni and colleagues report the associations of several biomarkers with renal outcomes in individuals with high-risk APOL1 genotypes.
Etty, Kruzel-Davila, Karl, Skorecki
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