Results 291 to 300 of about 451,806 (340)
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Lost in transition: Challenges in the expanding field of adult genetics

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2006
AbstractIt is increasingly clear that medical genetics has broad relevance in adult clinical medicine. More adult patients with genetic conditions are being recognized, genetic testing for adult‐onset genetic conditions is expanding, and children with genetic conditions are now more likely to survive to adulthood. While the number of patients who could
Matthew R.G. Taylor   +2 more
openaire   +3 more sources

Adolescents' Transition to Self-Management of a Chronic Genetic Disorder

Qualitative Health Research, 2008
Self-management of chronic illness requires acquisition of self-care skills such as seeking knowledge, adhering to recommendations, practicing healthy behaviors, and life-long self-surveillance. This article describes the core problem and psychosocial processes by which parents transfer, and children take on, the responsibility for managing a chronic ...
Barbara A. Bernhardt   +3 more
openaire   +3 more sources

Molecular genetic aspects of prostate transition zone lesions

Urology, 2003
The prostate is a composite exocrine gland divided into four zones: anterior fibromuscular stroma, peripheral zone (PZ), central zone, and preprostatic tissue. The preprostatic tissue is the smallest, but most complex, prostate zone. Its main component is a cylindrical, smooth, muscular sphincter. Inside this muscle, are tiny periurethral glands.
Z̆arko Zeljko   +2 more
openaire   +3 more sources

The importance of genetic counselling for turner syndrome transition

European Child & Adolescent Psychiatry
The healthcare transition (HCT) is the process of planning, monitoring, and adjusting the clinical management from children's care to adult specialists. Although this practice is common for all children, it is especially crucial (and challenging) for those with chronic disorders and genetic conditions that also involve mental health issues, requiring a
Eva M. Lafuente Villarreal   +6 more
openaire   +2 more sources

Multifocality of transitional cell carcinoma results from genetic instability of entire transitional epithelium

Urology, 1999
Multifocality of transitional cell carcinoma (TCC) has been attributed to seeding of exfoliated tumor cells or to a general sensitivity of the entire urothelium to carcinogenic stimuli. By contrast, TCC has been shown to evolve as a consequence of genetic defects and chromosomal instability.
Michael Marberger   +6 more
openaire   +3 more sources

An asymptotic formula for the transition density of random genetic drift

Journal of Applied Probability, 1978
Stochastic models in population genetics which lead to diffusion equations are considered. A geometric formula for the asymptotic expansions of the fundamental solutions of these equations is presented. Specifically, the random genetic drift process of one-locus theory and the Ohta–Kimura model of two-locus di-allelic systems with linkage are studied ...
openaire   +2 more sources

Using human genetics to improve safety assessment of therapeutics

Nature Reviews Drug Discovery, 2023
Keren Carss   +2 more
exaly  

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