Results 121 to 130 of about 2,228,086 (285)

Current transition management of adolescents and young adults with allergy and asthma: a European survey. [PDF]

open access: yesClin Transl Allergy, 2020
Khaleva E   +20 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

A Conceptual Framework for Optimizing Performance in Sustainable Supply Chain Management and Digital Transformation towards Industry 5.0

open access: yesMathematics
The economic growth of developed or emerging countries through globalization has prompted them to increase their supply chain performance. A large number of concepts, tools, and methodologies have been proposed in support of this performance improvement.
Paul-Eric Dossou   +2 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Gospel or curse: the impact of religious beliefs on energy poverty in rural China

open access: yesHumanities & Social Sciences Communications
Energy poverty, especially in rural areas, has become a central focus of scholarly and policy discussions. However, there is a significant gap in understanding the impact of religious beliefs on this phenomenon.
Jie Dong, Yanjun Ren, Thomas Glauben
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

The Slow Pace of Green Transformation: Underlying Factors and Implications

open access: yesEnergies
Concerns about climate change are a hot topic in the current debate about a sustainable future, and despite more than 30 years of international conferences, including the Intergovernmental Panel on Climate Change (IPCC) and the United Nations Climate ...
Tessaleno Devezas   +3 more
doaj   +1 more source

On the Feasibility of "Twofold Transformation". Can Institutions of Sustainability Evolve in Transition Countries? [PDF]

open access: yes
This paper aims at explaining the role and importance of the evolution of institutions for sustainable agri-environments during the transition process by referring to agrienvironmental problems faced in Central and Eastern European countries.
Hagedorn, Konrad
core   +1 more source

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