Results 41 to 50 of about 10,680,380 (363)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Superconductivity in single-layer films of FeSe with a transition temperature above 100 K [PDF]

open access: yes, 2014
Key Laboratory of Artificial Structures and Quantum Control (Ministry of Education), Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
Jian-Feng Ge   +7 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Thermal Response in Cellulose Iβ Based on Molecular Dynamics

open access: yesComputational and Mathematical Biophysics, 2019
The structural details of cellulose I β were discussed according to molecular dynamics simulations with the GLYCAM-06 force field. The simulation outcomes were in agreement with previous experimental data, including structural parameters and hydrogen ...
Jiang Xuewei   +3 more
doaj   +1 more source

Glass transition temperature versus structure of polyamide 6: A flash-DSC study

open access: yes, 2017
The glass transition temperature ( T g ) is a crucial parameter for understanding the mechanical behavior of polyamide 6. It depends mainly on two aspects: hydration level and processing, i.e. the thermal history and the flow conditions.
E. Parodi, L. Govaert, G. Peters
semanticscholar   +1 more source

Influence of Network Structure on Glass Transition Temperature of Elastomers

open access: yesMaterials, 2016
It is generally believed that only intermolecular, elastically-effective crosslinks influence elastomer properties. The role of the intramolecular modifications of the polymer chains is marginalized.
K. Bandzierz   +5 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fe-based superconducting transition temperature modeling by machine learning: A computer science method.

open access: yesPLoS ONE, 2021
Searching for new high temperature superconductors has long been a key research issue. Fe-based superconductors attract researchers' attention due to their high transition temperature, strong irreversibility field, and excellent crystallographic symmetry.
Zhiyuan Hu
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Iron-based high transition temperature superconductors [PDF]

open access: yes, 2014
In a superconductor electrons form pairs and electric transport becomes dissipation-less at low temperatures. Recently discovered iron-based superconductors have the highest superconducting transition temperature next to copper oxides.
Xianhui Chen   +4 more
semanticscholar   +1 more source

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