Results 101 to 110 of about 349,406 (324)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
New perspective on youth migration: Motives and family investment patterns
Demographic Research, 2015 Background: Migration research commonly assumes that youth migrate as dependent family members or are motivated by current labor opportunities and immediate financial returns.
Jessica Heckert
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Transition trajectories from youth institutional care to adulthood
SHS Web of Conferences, 2018 The main trajectories of transitions have essential importance for a child and youth living in child long-term institutional care – moving from family care to institutional care, life in institution(s), and the second trajectory – transition from ...
Trapenciere Ilze
doaj +1 more source
Demographic Research, 2018 Objective: This study assesses whether frequency of residential mobility plays a role in the reproduction of socioeconomic inequality during the transition to adulthood based on two criteria: (1) selection - is there socioeconomic sorting into ...
Anne Clark
doaj +1 more source
A Developmental Perspective on College & Workplace Readiness [PDF]
, 2008 Reviews research on and identifies the physical, psychological, social, cognitive, and spiritual competencies high school graduates need to transition into college, the workplace, and adulthood.
Andrew Rivers +3 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A consensus statement on health-care transition of patients with childhood-onset chronic kidney diseases: providing adequate medical care in adolescence and young adulthood [PDF]
, 2018 Wataru Kubota +22 more
openalex +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source