Results 121 to 130 of about 349,406 (324)

Becoming an Adult in Europe: A Macro(/Micro)-Demographic Perspective [PDF]

open access: yes
Extreme cases in demography are important challenges for researchers, and the still important heterogeneity of European societies is a blessing for scholars interested in studying the importance of cultural and institutional factors. In the transition to
FFF1Francesco NNN1Billari
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Government Unconditional Cash Transfers and Safe Transitions To Adulthood In Malawi

open access: green, 2023
Monica Lambon‐Quayefio   +10 more
openalex   +1 more source

Comparing teen substance use in northern New Hampshire to rural use nationwide [PDF]

open access: yes, 2013
Using data administered in 2011 from the Carsey Institute’s Coös Youth Study and the National Survey on Drug Use and Health, this brief compares teen substance use patterns in New Hampshire’s most rural county to patterns among rural youth nationwide ...
Van Gundy, Karen T.
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Youth who "Age Out" of Foster Care: Troubled Lives, Troubling Prospects [PDF]

open access: yes, 2001
If foster children, in general, are a population at risk, youth who age out of the system may be even more so. Research suggests that without the extended support most families provide young people in the transition to adulthood, youth leaving foster ...
Richard Wertheimer
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Similarities and differences between two cohorts of young adults in Italy [PDF]

open access: yes
The paper analyses the results of a CATI survey, consisting on a representative national sample of 3083 young people of two different generations: the 23-27th and the 33-37th in the first half of 2004.
Letizia Mencarini   +2 more
core  

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