Results 61 to 70 of about 87,067,097 (283)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Changes in the Order of Family Life Events in 20th-Century Europe: A Cross-Regional Perspective
Historical Life Course Studies, 2017 This article analyzes the evolution of the sequencing of family life events in Europe during the second half of the 20th century using individual data from the European Social Survey and from the Generation and Gender Program.
Reto Burgin +2 more
doaj +1 more source
Process, outcome and experience of transition from child to adult mental healthcare : multiperspective study [PDF]
, 2010 Background Many adolescents with mental health problems experience transition of care from child and adolescent mental health services (CAMHS) to adult mental health services (AMHS).
Belling, Ruth +18 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
People’s autonomy and psychological well-being in the transition to adulthood a pathway analysis
, 2020 Referencias bibliográficas: • Adler A., Seligman M. E. P., (2016). Using wellbeing for public politic: theory, measurement, and recommendations. Int. J. Wellbeing 6 1–35. 10.5502/Ijw.V6i1.429 32285354 • Alivernini F., Cavicchiolo E., Manganelli S., (2019)
Arroyo Resino, Gema Delia +3 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Diabetes Experiences of Transition from Childhood to Adulthood Care
Florence Nightingale Journal of Nursing, 2022 Alireza Nikbakht Nasrabadi +1 more
doaj +1 more source