Results 41 to 50 of about 93,688 (260)

Liquid CO₂ Phase-Transition Rock Fracturing: A Novel Technology for Safe Rock Excavation

Applied Sciences, 2021
In order to determine the applicability of liquid CO2 phase-transition fracturing technology in rock mass excavations, the principles of CO2 phase-transition fracturing were analyzed, and field tests of liquid CO2 phase-transition fracturing were ...
Haoyue Sui, Tianming Su, Ruilin Hu, Ke Yang, Yaxing Cheng   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Spatial and temporal fluctuation of phytoplankton functional groups in a tropical reservoir - doi: 10.4025/actascibiolsci.v35i3.12988

Acta Scientiarum: Biological Sciences, 2013
Along the horizontal axis of reservoirs are generally recognized three zones (fluvial, transition and lacustrine) with distinct hydrodynamic and physical, chemical and biological properties.
Lívia Oliveira Ruiz Moreti, Luana Martos, Vânia Mara Bovo-Scomparin, Luzia Cleide Rodrigues   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The transitional zone and CNS regeneration

Journal of Anatomy, 1999
Most nerves are attached to the neuraxis by rootlets. The CNS–PNS transitional zone (TZ) is that length of rootlet containing both central and peripheral nervous tissue. The 2 tissues are separated by a very irregular but clearly defined interface, consisting of the surface of the astrocytic tissue comprising the central component of the TZ. Central to
openaire   +4 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Magma-poor continent–ocean transition zones of the southern North Atlantic: a wide-angle seismic synthesis of a new frontier [PDF]

Solid Earth
Magma-poor rifted margins, and their corresponding potential zones of exhumed serpentinized mantle, represent a unique class of tectonic boundaries with enormous promise for advancing the energy transition, such as with hydrogen production and carbon ...
J. K. Welford
doaj   +1 more source

Transit Zones

, 2012
Transit Zones interrogates conceptual and theoretical issues concerning the notion of nomadic transience, where movement, stasis and the peripatetic state converge with time. This photographic based research examines the relationship between the still frame and the moving image and the visual metamorphosis from realism to abstraction in the spatial and
openaire   +2 more sources