Results 101 to 110 of about 394,621 (349)

Emergency Crisis Services for Psychiatric Boarder Patients at Central Vermont Hospital ED [PDF]

open access: yes, 2017
Purpose: This project’s aim was to reduce the length of emergency department (ED) stays for psychiatric boarder patients at Central Vermont Medical Center (CVMC) and prevent unnecessary psychiatric inpatient admissions through access to psychiatric ...
Burzynski, Ann E
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Cancellation of Nongroup Health Insurance Policies [PDF]

open access: yes, 2013
Congress has expressed interest in health insurance cancellations, in light of media reports stating that individuals have received cancellation letters.
Fernandez, Bernadette, Mach, Annie L
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Financing Housing Supports for Youth Transitioning Out of Foster Care [PDF]

open access: yes, 2009
This strategy brief, written by The Finance Project with support from the Foster Care Work Group (FCWG), one of three work groups of the Youth Transition Funders Group (YTFG), explores strategies for financing supports and services that help foster youth
Roxana Torrico, Soumya Bhat
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Investing in primary care as the bridge for transitional care [PDF]

open access: bronze, 2010
Finella Craig   +3 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

PalliSupport – The development, feasibility and implementation of a transitional integrated care pathway for older patients with palliative care needs

open access: yesInternational Journal of Integrated Care, 2019
Introduction - Marjon van Rijn (5 minutes): For the development, implementation and evaluation of a transitional integrated care pathway for older patient with palliative care needs we used the Medical Research (MRC) Framework.
Marjon van Rijn   +3 more
doaj   +1 more source

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