Results 71 to 80 of about 4,245,243 (252)

Pediatricians’ Perspectives on Introducing Transitional Care into Handover Between Pediatric Intensive Care Units and General Wards [PDF]

Jianlin Ji,1,* Liling Yang,2,* Hanlin Yang,1 Chengxi Zeng,1 Wenjuan Tang,2 Qunfeng Lu1,3 1School of Nursing, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Nursing Department, Children’s Hospital of Shanghai, School of ...
Yang H, Zeng C, Yang L, Ji J, Tang W, Lu Q   +5 more
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Transitional Justice’s Expanding Empire: Reasserting the Value of the Paradigmatic Transition? [PDF]

, 2011
Transitional justice studies increasingly apply to processes of truth, restoration and accountability in contexts far removed from the paradigmatic transitions from authoritarianism or war to relatively liberal democracy on which the field wasinitially ...
McAuliffe, Padraig
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Romancing the Carer - Intimate Relationships and Family Caring

, 2017
The topic of sexuality and romantic intimacy is not an easy one for many to discuss; in particular is it is often seen as secondary to the difficulties being faced in other aspects of life and in the relationship.
Care Alliance Ireland
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Effectiveness of transitional care interventions in patients with serious illness and their caregivers: a systematic review and metanalysis of randomized controlled trial

BMC Nursing
Background Patients with serious illnesses require continuous care from professionals in multiple settings. The care transition interventions aim to promote the safe and timely transfer of patient care across settings through several components including
Marco Di Nitto, Angela Durante, Gabriele Caggianelli, Jacopo Fiorini, Silvia Sferrazza, Kusumam Pampoorickel, Roberto Accettone, Dhurata Ivziku, Daniela D’Angelo   +8 more
doaj   +1 more source

Transitional Care Program in Reducing Acute Hospital Utilization in Singapore

(1) Background: The evidence to support transitional care in reducing acute hospital utilization is variable. Despite changes in the healthcare landscape with a rapidly aging population, there is a lack of local and regional studies to evaluate the ...
Mui Hua Jean Lee, Chong Yau Ong, Kar Kwan Sandra Joanne Ng, Pei Yoke Tay, Jun Jie Angus Ng   +4 more
core   +1 more source

Stakeholders’ experiences and perception on transitional care initiatives within an integrated care project in Belgium: a qualitative interview study

, 2023
BACKGROUND: In 2015, a plan for integrated care was launched by the Belgium government that resulted in the implementation of 12 integrated care pilot project across Belgium.
Goderis, Geert, Verbeek, H., Verbeek, Hilde, Fakha, A., van Pottelbergh, Gijs, Deschodt, Mieke, Leithaus, M., Flamaing, J., Fakha, Amal, van Pottelbergh, G., Deschodt, M., Leithaus, Merel, Flamaing, Johan, Goderis, G.   +13 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source