Results 71 to 80 of about 77,380 (309)

Transitional care of older ethnic minority patients: An integrative review

, 2023
AimsTo critically synthesize the empirical literature on practice in transitional care and how to meet the care needs of older ethnic minority populations who discharged from hospital to community.
Hayter, Mark, Dolu, İlknur, Serrant, Laura   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Transitional care programs for older adults moving from hospital to home in Canada: A systematic review of text and opinion.

PLoS ONE
BackgroundInvesting in transitional care programs is critical for ensuring continuity of health and coordinated care for older adults transitioning across health settings.
Brittany V Barber, Emily E Gregg, Emily K Drake, Marilyn Macdonald, Madison Hickey, Chloe Flynn, Elaine Moody, Sarah M Gallant, Erin McConnell, Lori E Weeks   +9 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Challenges and Adaptive Strategies in Transitional Care During COVID-19: A Qualitative Study of Nurses’ Experiences in Japan

Nursing Reports
Background/Objectives: To examine shifts and challenges in transitional care practices during COVID-19 and the adaptive strategies developed by Transitional Care Nurses (TCNs) in response. Methods: A qualitative descriptive study was conducted using semi-
Yuka Sumikawa, Noriha Tanaka, Noriko Yamamoto-Mitani   +2 more
doaj   +1 more source

Transitional Care Program in Reducing Acute Hospital Utilization in Singapore

(1) Background: The evidence to support transitional care in reducing acute hospital utilization is variable. Despite changes in the healthcare landscape with a rapidly aging population, there is a lack of local and regional studies to evaluate the ...
Mui Hua Jean Lee, Chong Yau Ong, Kar Kwan Sandra Joanne Ng, Pei Yoke Tay, Jun Jie Angus Ng   +4 more
core   +1 more source

The Nurse Practitioner Role in United States of America within Transitional Care and Care Coordination Models

, 2018
coordination models which have been operationalized within targeted populations that havefiscally reduced healthcare costs in the USA. A context of future globalization application ofthese emerging models will be discussed.Background The USA healthcare ...
Mola, Ana
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Research advances on transitional care of patients transferred from ICU

Huli yanjiu, 2019
Abstract This article expounded the concept of transitional care of patients transferred from ICU,the specific content and significance of ICU transitional care,and the research status quo of transitional care of patients transferred from ICU in China,in
台瑞, 方芳, 杨富
doaj