Results 301 to 310 of about 82,828 (358)

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

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Transitional cell carcinoma.

American Journal of Roentgenology, 1993
contrast-enhanced CTscanshowed themasswaswithinthecollecting system (Fig.1B).Thebladder andure-terwerenormal, andresultsofcytologic examination oftheurinewerenormal. Afternephroureterectomy, abulky,ses-sile,papillary tumor arising fromtheuroepithelium wasfoundintheupperpole.Microscopy revealed focalinvasionoftherenalparenchyma, andthefinalpathologic ...
M H, Lev, F S, Chew
openaire   +2 more sources

A transitional cell carcinoma cell line

In Vitro, 1978
A transitional cell carcinoma cell line, COLO 232, was derived from a primary urinary bladder tumor in a Caucasian male. In culture, COLO 232 retained distinct uroepithelial phenotypic traits and produced both carcinoembryonic antigen and adrenocorticotropic hormone. COLO 232 had a chromosome mode of 58 and retained the X and Y chromosomes.
G E, Moore, R T, Morgan, L A, Quinn, L K, Woods   +3 more
openaire   +2 more sources

Upper-tract transitional cell carcinoma

Urology, 1997
Advances in ureteroscopic techniques have made it possible to treat many upper-tract tumors conservatively. Such treatment has demonstrated acceptable survival and renal preservation in high-risk patients, particularly those with a solitary kidney, bilateral tumors, poor renal function, or prohibitive operative risk.
E R, Tawfiek, D H, Bagley
openaire   +2 more sources

Parafallopian Tube Transitional Cell Carcinoma

Gynecologic Oncology, 2002
Transitional cell carcinoma (TCC) has recently been acknowledged as a distinct histologic pattern of the uncommon primary fallopian tube carcinoma. However, rare cases of TCC that are closely associated to the extraluminal portion of the tube remain widely unrecognized.We present a left adnexal high-grade TCC in a 56-year-old postmenopausal woman with ...
Gladell P, Paner, Miguel, Gonzalez, Hytham, Al-Masri, Donna Marie, Smith, Aliya N, Husain   +4 more
openaire   +2 more sources

Zosteriform metastatic transitional cell carcinoma

International Journal of Dermatology, 2004
Presentation of metastatic nodules in a dermatomal distribution is very rare. We present the case of a 63‐year‐old woman with zosteriform metastasis secondary to transitional cell carcinoma of the bladder. Possible mechanisms of dissemination are discussed.
Christy A, Woodruff, Mojghan, Amrikachi, Sylvia, Hsu   +2 more
openaire   +2 more sources

Genetics of transitional cell carcinoma

Seminars in Surgical Oncology, 1992
AbstractSeveral models of genetic events which define the origin and progression of human tumors have been elucidated over the last several years. These models suggest that the study of tumors at the level of both the chromosome and the gene can be useful in elucidating molecular events in tumor progression and in determining the biologic behavior of ...
E A, Klein, R S, Chaganti
openaire   +2 more sources

Transitional cell carcinoma of bladder originating from transitional cell carcinoma of anus

Urology, 1983
A unique case of transitional cell carcinoma of the bladder with the primary being in the anus is reported. The patient presented with acute urinary retention from a large bladder tumor, which was thought to be primary to the bladder. Biopsy of the bladder revealed transitional cell carcinoma, microscopically indistinguishable from the primary ...
M, Edson, E, Colmenares
openaire   +2 more sources