Results 71 to 80 of about 211,772 (339)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Transitional Justice in Relationship to Public Sphere and Civil Society: Theoretical Approaches [PDF]

Polish Political Science Yearbook, 2018
The article presents the entitled fields in the framework of their mutual influence. The notion of the public sphere is valuable for understanding the role that civil society plays in transitional justice processes.
Edyta
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Argentinian Transitional Justice Process: Women Behind [PDF]

, 2013
In the Argentinian transitional justice process, women's issues were neglected by all the different mechanisms that attempted to redress the gross human rights violations perpetrated during the last military dictatorship. In other words, democracy failed
Zavala Guillen, A.L.
core  

Transitional justice in times of 'exponential change': constructing normative frameworks fit for purpose - the importance of general international law [PDF]

, 2014
In the attempt to reformulate transitional justice to include broader rule of law approaches, there are substantial challenges in ensuring institutional, normative, and policy coherence.
French, Duncan, Samuel, Katja
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Charting Uncharted Waters: Participatory Budgeting as a Novel Transitional Justice Guarantee of Non-Recurrence of the Conflict in Colombia?

GIGAPP Estudios Working Papers, 2017
After fifty years of war, Colombia is about to start the implementation of an ambitious peace deal between the Government and the FARC-EP guerrilla. The final Peace Agreement between the parties surpass transitional justice measures implemented before ...
Dian Dajer Barguil
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Transitional Justice

, 2010
This special issue of the ISJ reviews key aspects of transitional justice as a desirable solution to the problem of terrorism in the Occupied Territories. In the introductory article, authors seek to develop a specific profile of transitional justice that is appropriate and feasible for the Occupied Territories (OT), in light of the experience of other
  +5 more sources

Failing Victims? The Limits of Transitional Justice in Addressing the Needs of Victims of Violations [PDF]

, 2017
Transitional justice represents itself as both a discourse and practice that exists primarily to support victims of human rights violations and gains its moral legitimacy from the fact that victims are deserving and the claim that transitional justice ...
Robins, Simon
core