Results 201 to 210 of about 3,292 (264)

The Real‐World Safety Profile of Immune Checkpoint Inhibitors in Melanoma: FAERS Pharmacovigilance Analysis Complemented by Randomized Trial Evidence

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Melanoma can be effectively treated with immune checkpoint inhibitors (ICIs), but information regarding the risks of treatment‐related adverse events (trAEs), immune‐related adverse events (irAEs), and real‐world adverse events (AEs) is scarce.
Yiwei Chen   +3 more
wiley   +1 more source

Upper Bounds on the Minimum Size of Feedback Arc Set of Directed Multigraphs With Bounded Degree

open access: yesJournal of Graph Theory, Volume 112, Issue 4, Page 421-432, August 2026.
ABSTRACT An oriented multigraph is a directed multigraph without directed 2‐cycles. Let fas ( D ) denote the minimum size of a feedback arc set in an oriented multigraph D. In several papers, upper bounds for fas ( D ) were obtained for oriented multigraphs D with maximum degree upper‐bounded by a constant.
Gregory Gutin   +3 more
wiley   +1 more source

Balance and Baselines: An Impossibility Theorem and an Axiomatisation of Additive Aggregation

open access: yesJournal of Multi-Criteria Decision Analysis, Volume 33, Issue 2, August 2026.
ABSTRACT A feature in many multicriteria problems is a preference for ‘balance’, understood as achieving a desired distribution (e.g., equality or target proportions) of resources across stakeholders or conceptual categories. This paper presents a normative exploration of the implications of balance preferences when baselines are uncertain or contested.
Alec Morton, Lars Peter Østerdal
wiley   +1 more source

Catheter‐Based Therapies for Intermediate‐High Risk Pulmonary Embolism: A Protocol for a Systematic Review With Bayesian Pairwise and Network Meta‐Analyses

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Intermediate‐high risk pulmonary embolism (PE) represents a clinically challenging subgroup of acute PE, characterized by right ventricular dysfunction and increased risk of hemodynamic deterioration despite treatment with anticoagulation therapy.
Jacob Hindborg Hovmann   +11 more
wiley   +1 more source

The Effect of Canagliflozin Dose on Renal and Cardiovascular Outcomes in Type 2 Diabetes and High Cardiovascular Risk

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7083-7093, August 2026.
ABSTRACT Introduction Pharmacokinetic data suggest a potential dose‐dependent effect of sodium–glucose co‐transporter‐2 (SGLT‐2) inhibitors on surrogate markers of efficacy, but the impact of SGLT‐2 inhibitor dose on renal and cardiovascular outcomes remains uncertain.
Elias John Elenjickal   +5 more
wiley   +1 more source

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