Results 141 to 150 of about 140,835 (316)

A preliminary study of the thermal strain experienced by dive support boat personnel. [PDF]

open access: yesInt J Circumpolar Health, 2023
Saunders S   +4 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The Kepler Follow-up Observation Program

open access: yes, 2010
The Kepler Mission was launched on March 6, 2009 to perform a photometric survey of more than 100,000 dwarf stars to search for terrestrial-size planets with the transit technique. Follow-up observations of planetary candidates identified by detection of
Batalha, Natalie M.   +16 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Study on the Nonlinear Vibration Characteristic of Bending-torsional Coupled Single-stage Gear

open access: yesJixie chuandong, 2019
Taking spur gear pair as the research object, a 6-DOF coupled bending-torsion nonlinear vibration model including time-varying meshing stiffness, comprehensive error, backlash and input torque is established. Based on the bifurcation diagram and Poincare
Rongju Liu   +3 more
doaj  

Detecting New Planets in Transiting Systems

open access: yes, 2006
I present an initial investigation into a new planet detection technique that uses the transit timing of a known, transiting planet. The transits of a solitary planet orbiting a star occur at equally spaced intervals in time.
Steffen, Jason H.
core  

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