Results 201 to 210 of about 84,662 (294)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Transitions [PDF]

Nursing for Women's Health, 2012
openaire   +4 more sources

Analyzing anomalous events in passageways with high-frequency ship signals. [PDF]

PLoS One
Chico C, Cordel MOI, Mariasingham MJ, Tan ES.   +3 more
europepmc   +1 more source

OBSERVATIONS OF THE TRANSIT OF MERCURY, MAY 9, 1891, AT MOUNT HAMILTON [PDF]

, 1891
E. S. Holden, James E. Keeler
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Temporal trend of microenvironmental time-activity patterns of the Seoul population from 2004 to 2022 and its potential impact on exposure assessment. [PDF]

J Expo Sci Environ Epidemiol
Kim D, Guak S, Lee K.
europepmc   +1 more source

On the best Mode of undertaking a Discussion of the Observations of Contact to be made at the approaching Transit of Venus [PDF]

, 1882
David Gill
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Multi-Zone Visco-Node-Pore Sensing: A Microfluidic Platform for Multi-Frequency Viscoelastic Phenotyping of Single Cells. [PDF]

Adv Sci (Weinh)
Lai A, Hinz S, Dong A, Lustig M, LaBarge MA, Sohn LL.   +5 more
europepmc   +1 more source

The transit of ions in the electric arc

, 1905
A. A. CAMPBELL SWINTON
openalex   +1 more source