Results 201 to 210 of about 140,835 (316)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Biochemically Programmable Isothermal PCR. [PDF]
Kim M, Ravisankar V, Hassan YA, Ugaz VM.
europepmc +1 more source
Sideways maneuvers enable narrow aperture negotiation by free-flying hummingbirds.
Badger MA +4 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A first look at rocky exoplanets with JWST. [PDF]
Kreidberg L, Stevenson KB.
europepmc +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Modeling Functional Connectivity for Bears Among Spawning Salmon Waterways in Haíɫzaqv (Heiltsuk) Territory, Coastal British Columbia. [PDF]
Mihalik I +5 more
europepmc +1 more source
Discovery and Characterization of an Eccentric, Warm Saturn Transiting the Solar Analog TOI-4994 [PDF]
Romy Rodríguez Martínez +48 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source

