Results 241 to 250 of about 363,457 (364)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

A first look at rocky exoplanets with JWST. [PDF]

open access: yesProc Natl Acad Sci U S A
Kreidberg L, Stevenson KB.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

WASP-50 b: a hot Jupiter transiting a moderately active solar-type star [PDF]

open access: bronze, 2011
M. Gillon   +24 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Biochemically Programmable Isothermal PCR. [PDF]

open access: yesAdv Sci (Weinh)
Kim M, Ravisankar V, Hassan YA, Ugaz VM.
europepmc   +1 more source

TRANSITIONAL CARE [PDF]

open access: yesJournal of Social Work Education, 2008
Mary, Naylor, Stacen A, Keating
openaire   +2 more sources

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