Results 31 to 40 of about 84,662 (294)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Transits maghrébins à Istanbul. Trajectoires, profils et stratégies

open access: yesRevue des Mondes Musulmans et de la Méditerranée, 2007
Since the beginning of the 1990’s, Istanbul has become a focal point, both polarizing and re-dispatching the flows in the international transit migration system set up between Europe and poor countries.
Jean-François Pérouse
doaj   +1 more source

New observations and transit solutions of the exoplanets HAT-P-54b and WASP-153b [PDF]

open access: yesSerbian Astronomical Journal, 2019
We present photometric observations of the newly-discovered transiting exoplanets HAT-P-54b and WASP-153b with the Rozhen 2 m telescope. As a result we improved their periods.
Kjurkchieva Diana   +2 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

En Tránsito: Desplazamientos Nimios en el Cine Latinoamericano (2000-2010) On the Way: Trivial Travelling in Latin American Cinema (2000-2010)

open access: yesAisthesis, 2010
Este artículo busca poner en escena y analizar ciertos tránsitos, heterogéneos en su consumación, en el cine latinoamericano (2000-2010). Indaga, a partir de algunas reflexiones de Marc Augé, Isaac Joseph y Michel de Certau, las posibilidades de tránsito,
Luis Valenzuela Prado
doaj  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

The Colorado Ultraviolet Transit Experiment Mission Overview

open access: yesThe Astronomical Journal, 2023
Atmospheric escape is a fundamental process that affects the structure, composition, and evolution of many planets. The signatures of escape are detectable on close-in, gaseous exoplanets orbiting bright stars, owing to the high levels of extreme ...
Kevin France   +20 more
doaj   +1 more source

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