Results 151 to 160 of about 318,913 (308)
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Reweaving the Tapestry of Intertextuality. The Italian Translations of Keats's "When I Have Fears"
As Percy Bysshe Shelley pointed out in “A Defence of Poetry” (1821), all translations inevitably result in a loss. In particular, much is at stake in the case of poetry, insofar as meaning is tightly connected with form, and rhythmical and metrical ...
M. Canani
core
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
http://www.estranslation.net/it/index.php?lang_home=true 61 events, more than 100 guests and speakers; poets, translators, writers and critics, actors, musicians, subtitlers, scholars, film-makers, professional operators, social operators, articulated ...
Borek J., Hornig D., MIGLIO, Camilla
core
Cosmin reporting guideline for studies on measurement properties of patient-reported outcome measures and its explanation and elaboration document: translation into Brazilian Portuguese. [PDF]
de Arruda GT +4 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Interview: Institute of Modern Language Research
The (re)launch of the Institute of Modern Language Research (IMLR) at Senate House on 7 December was a great success, and I was delighted to be offered the opportunity to share a panel with Barry Smith to present the interdisciplinary challenges afforded
Charles Forsdick
core
Climate change and infectious diseases: translating evidence into action. [PDF]
Shi X +7 more
europepmc +1 more source

