Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer +8 more
wiley +1 more source
Systematic meta-review on migrant healthcare access: Language barriers and the role of translation. [PDF]
Díaz-Millón M, Olvera-Lobo MD.
europepmc +1 more source
I. An account of the earthquakes in Sicilia, on the ninth and eleventh of January, 1692/3. Translated from an Italian letter from Sicily by the noble Vincentius Bonajutus, and communicated to the Royal Society by the learned Marcellus Malpighius, physician to his present Holineß [PDF]
Vincentius Bonajutus
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A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Coordinated hippocampal-entorhinal representations support human context-dependent spatial navigation. [PDF]
Lv P +6 more
europepmc +1 more source
A Different Perspective on the Solid Lubrication Performance of Black Phosphorous: Friend or Foe?
Researchers investigate black phosphorous (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli +5 more
wiley +1 more source
Cross-dialectal Arabic translation: comparative analysis on large language models. [PDF]
Beidas A +4 more
europepmc +1 more source
IX. A memoir on the best method of measuring time at sea, which obtained the double prize adjudged by the royal Academy of Sciences; containing the description of the longitude watch presented to his majesty the 5th of August 1766. Translated from the French by Mr. T. S. E
Malini Roy
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Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani +4 more
wiley +1 more source
Promoter-proximal transcription-translation coupling controls early transcription in Escherichia coli. [PDF]
Park S +6 more
europepmc +1 more source

