Results 171 to 180 of about 3,070,291 (402)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Translating cell biology of ageing? On the importance of choreographing knowledge

, 2020
Tiago Moreira
openalex   +2 more sources

New approach to engineer translation systems for synthetic biology [PDF]

, 2017

openalex   +1 more source

[Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation [PDF]

, 2022
Huan Qian, Yihan Shan, Ruicheng Gong, Danfeng Lin, Mengwen Zhang, Chen Wang, Lu Wang   +6 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology [PDF]

, 2013
Derek J. Hausenloy, Hans Erik Bøtker, Gianluigi Condorelli, Péter Ferdinandy, David García‐Dorado, Gerd Heusch, Sandrine Lecour, Linda W. van Laake, Rosalinda Madonna, Marisol Ruiz‐Meana, Rainer Schulz, Joost P. G. Sluijter, Derek M. Yellon, Michel Ovize   +13 more
openalex   +1 more source

10 Years of GWAS Discovery: Biology, Function, and Translation.

American Journal of Human Genetics, 2017
P. Visscher, N. Wray, Qian Zhang, P. Sklar, M. McCarthy, M. Brown, Jian Yang   +6 more
semanticscholar   +1 more source

Intracellular mRNA transport and localized translation

Nature reviews. Molecular cell biology, 2021
Sulagna Das, Maria Vera, V. Gandin, R. Singer, Evelina Tutucci   +4 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

6-HYDROXY-L-NICOTINE INHIBITS THE AGGREGATION OF AΒ1-42 IN A549 AND MCF7 CELL CULTURES

IBRO Neuroscience Reports, 2023
Lucian Hritcu, Adrian Tiron, Crina Elena Tiron, Paula Alexandra Stache   +3 more
doaj   +1 more source