Results 191 to 200 of about 2,947,154 (398)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Translating Volatile Anesthetic-induced Cardioprotection into Systems Biology [PDF]

, 2011
Christopher Lotz, Franz Kehl
openalex   +1 more source

Intracellular mRNA transport and localized translation

Nature reviews. Molecular cell biology, 2021
Sulagna Das, Maria Vera, V. Gandin, R. Singer, Evelina Tutucci   +4 more
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Translating cell biology of ageing? On the importance of choreographing knowledge [PDF]

, 2020
Tiago Moreira
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

6-HYDROXY-L-NICOTINE INHIBITS THE AGGREGATION OF AΒ1-42 IN A549 AND MCF7 CELL CULTURES

IBRO Neuroscience Reports, 2023
Lucian Hritcu, Adrian Tiron, Crina Elena Tiron, Paula Alexandra Stache   +3 more
doaj   +1 more source

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies [PDF]

, 2014
Brigitte C. Widemann, Maria T. Acosta, Sylvia Ammoun, Allan J. Belzberg, André Bernards, Jaishri O. Blakeley, Antony Bretscher, Karen Cichowski, D. Wade Clapp, Eva Dombi, D. Gareth Evans, Rosalie E. Ferner, Cristina Fernández‐Valle, Michael J. Fisher, Marco Giovannini, David H. Gutmann, C. Oliver Hanemann, Robert F. Hennigan, Susan Huson, David A. Ingram, Joe Kissil, Bruce R. Korf, Eric Legius, Roger J. Packer, Andrea I. McClatchey, Frank McCormick, Kathryn N. North, Minja Pehrsson, Scott R. Plotkin, Vijaya Ramesh, Nancy Ratner, Susann Schirmer, Larry S. Sherman, Elizabeth K. Schorry, David A. Stevenson, Douglas R. Stewart, Nicole J. Ullrich, Annette Bakker, Helen Morrison   +38 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Preventing Pain Requires Translating Biology into Social Change [PDF]

, 2014
Jordan F. Karp
openalex   +1 more source