Results 201 to 210 of about 2,947,154 (398)

Translational plant biology [PDF]

Journal of Integrative Plant Biology, 2015
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Research Translation and Emerging Health Technologies: Synthetic Biology and Beyond [PDF]

, 2016
Sarah Chan
openalex   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Asteroids, Ophiuroids, and Echinoids of the English Antarctic Expedition of 1907–1909: A translation of Astéries, Ophiures, et Échinides de l'Expédition Antarctique Anglaise de 1907-1909. British Antarctic Expedition 1907-1909, Reports on the Scientific Investigations 2 (Biology), 4: 25–66, London: W. Heinemann

, 1911
R. D. Koehler
openalex   +2 more sources

Emerging therapies for acute myeloid leukemia: translating biology into the clinic [PDF]

, 2017
Simon Kavanagh, Tracy Murphy, Arjun Law, Dana Yehudai, Jenny Ho, Stephen Chan, Aaron D. Schimmer   +6 more
openalex   +1 more source

Genetics of coronary artery disease: discovery, biology and clinical translation

Nature reviews genetics, 2017
A. Khera, S. Kathiresan
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Patient and public involvement in preclinical and medical research: Evaluation of an established programme in a Discovery‐Based Medical Research Institute

Health Expectations
Background and Context Involving people with lived experience of health conditions and the public (consumers) in health research is supported by policy, practice and research funding schemes.
Robyn A. Smith, Judith Slocombe, Jo Cockwill, Kathy Minas, George Kiossoglou, Katya Gray, William Lawrence, Michelle Iddles, Clare Scott, Lorraine A. O'Reilly   +9 more
doaj   +1 more source