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Progress and challenges in translating the biology of atherosclerosis
Nature, 2011Atherosclerosis is a chronic disease of the arterial wall, and a leading cause of death and loss of productive life years worldwide. Research into the disease has led to many compelling hypotheses about the pathophysiology of atherosclerotic lesion formation and of complications such as myocardial infarction and stroke.
Peter Libby +2 more
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Translating biology into clinic: the case of glioblastoma
Current Opinion in Cell Biology, 2009GBM, the most common and malignant primary tumor of the CNS, is characterized by exponential growth and diffuse invasiveness. Although the diverse causative genotypes that give rise to a inhomogeneous histological phenotype are well defined, effective therapy inducing tumor cell apoptosis has not been established so far.
Adrian Merlo, Maddalena M. Lino
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The neurovascular unit and systemic biology in stroke — implications for translation and treatment
Nature Reviews Neurology, 2022S. Tiedt +5 more
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Translation, genetics and cell biology
Trends in Genetics, 1987time of macronuclear development, which is measured in hours in many ciliates. As noted above, in Oxytriclm the deletion-rejoining must be pre-[ cise. However, variation in the sites of rejoining of certain lESs has been seen in Tetrahymena (reviewed in Ref. 6) and Paramecium (J. Forney and E. Blackburn, submitted). Klobutcher et al. note that lESs are
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Towards clinical translation of FLASH radiotherapy
Nature Reviews Clinical Oncology, 2022M. Vozenin, J. Bourhis, M. Durante
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Clinical Translation of Discoveries in Cardiomyocyte Biology
2021During the last three decades, there has been significant progress in our understanding of the cellular and molecular basis of normal functions in cardiomyocytes as well as the alterations in the homeostatic mechanisms that lead to pathological states in these cells.
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A misconception in biology: Amino acids and translation
Journal of Research in Science Teaching, 1985AbstractA persistent error has been observed among students in introductory biology and genetics. In interviews and examinations, many students express the belief that amino acids are produced by genetic translation (protein synthesis). The evidence suggests that at least four underlying factors contribute to error occurrence: (1) strong word ...
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Bacterial therapies at the interface of synthetic biology and nanomedicine.
Nature Reviews Bioengineering, 2023Jaeseung Hahn +5 more
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Cell-free transcription-translation: engineering biology from the nanometer to the millimeter scale.
Current Opinion in Biotechnology, 2019David Garenne, V. Noireaux
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Systems biology and translational research
Journal of Critical Care, 2005Edmund Neugebauer, Gilles Clermont
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